Ursula H Jakob
Patricia S Yaeger Collegiate Professor of Molecular, Cellular and Developmental Biology
Professor of Molecular, Cellular and Developmental Biology
College of Literature, Science, and the Arts
Professor of Biological Chemistry
[email protected]

Available to mentor

Ursula H Jakob
Professor
  • Recent Publications
  • Recent Publications See All Publications
    • Journal Article
      Early life changes in histone landscape protect against age-associated amyloid toxicities through HSF-1-dependent regulation of lipid metabolism.
      Oleson BJ, Bhattrai J, Zalubas SL, Kravchenko TR, Ji Y, Jiang EL, Lu CC, Madden CR, Coffman JG, Bazopoulou D, Jones JW, Jakob U. Nat Aging, 2024 Jan; 4 (1): 48 - 61. DOI:10.1038/s43587-023-00537-4
      PMID: 38057386
    • Journal Article
      From guide to guard-activation mechanism of the stress-sensing chaperone Get3.
      Ulrich K, Farkas Á, Chan O, Katamanin O, Schwappach B, Jakob U. Mol Cell, 2022 Sep 1; 82 (17): 3226 - 3238.e7. DOI:10.1016/j.molcel.2022.06.015
      PMID: 35839781
    • Journal Article
      Quality Control: Maintaining molecular order and preventing cellular chaos.
      Neal S, Ohtake F, Cuervo AM, Hegde RS, Jakob U, Lazarou M, Gilbert WV, Chen ZJ, Tooze SA, Haber JE, Walters KJ, Hartl FU. Mol Cell, 2022 Apr 21; 82 (8): 1390 - 1397. DOI:10.1016/j.molcel.2022.04.002
      PMID: 35452608
    • Journal Article
      Copper Induces Protein Aggregation, a Toxic Process Compensated by Molecular Chaperones.
      Zuily L, Lahrach N, Fassler R, Genest O, Faller P, Sénèque O, Denis Y, Castanié-Cornet M-P, Genevaux P, Jakob U, Reichmann D, Giudici-Orticoni M-T, Ilbert M. mBio, 2022 Apr 26; 13 (2): e0325121 DOI:10.1128/mbio.03251-21
      PMID: 35289645
    • Journal Article
      Targeted protein degradation: from small molecules to complex organelles-a Keystone Symposia report.
      Cable J, Weber-Ban E, Clausen T, Walters KJ, Sharon M, Finley DJ, Gu Y, Hanna J, Feng Y, Martens S, Simonsen A, Hansen M, Zhang H, Goodwin JM, Reggio A, Chang C, Ge L, Schulman BA, Deshaies RJ, Dikic I, Harper JW, Wertz IE, Thomä NH, Słabicki M, Frydman J, Jakob U, David DC, Bennett EJ, Bertozzi CR, Sardana R, Eapen VV, Carra S. Ann N Y Acad Sci, 2022 Apr; 1510 (1): 79 - 99. DOI:10.1111/nyas.14745
      PMID: 35000205
    • Journal Article
      Polyphosphate drives bacterial heterochromatin formation.
      Beaufay F, Amemiya HM, Guan J, Basalla J, Meinen BA, Chen Z, Mitra R, Bardwell JCA, Biteen JS, Vecchiarelli AG, Freddolino PL, Jakob U. Sci Adv, 2021 Dec 24; 7 (52): eabk0233 DOI:10.1126/sciadv.abk0233
      PMID: 34936433
    • Journal Article
      Induction of the reactive chlorine-responsive transcription factor RclR in Escherichia coli following ingestion by neutrophils.
      Königstorfer A, Ashby LV, Bollar GE, Billiot CE, Gray MJ, Jakob U, Hampton MB, Winterbourn CC. Pathog Dis, 2021 Jan 9; 79 (1): DOI:10.1093/femspd/ftaa079
      PMID: 33351093
    • Journal Article
      Thiol-based switching mechanisms of stress-sensing chaperones.
      Ulrich K, Schwappach B, Jakob U. Biol Chem, 2021 Feb 23; 402 (3): 239 - 252. DOI:10.1515/hsz-2020-0262
      PMID: 32990643