George A Mashour
Senior Associate Dean for Faculty and Faculty Development
Robert B Sweet Professor of Anesthesiology
Professor of Anesthesiology
Professor of Neurosurgery
Professor of Pharmacology
[email protected]

Available to mentor
George A Mashour
Professor
  • Qualifications
  • Center Memberships
  • Research Overview
  • Recent Publications
    • Qualifications
    • MD, PhD
      Georgetown University, Washington D.C.
    Center Memberships
    • Center Member
      Center for Integrative Research in Critical Care
    Research Overview

    Multidisciplinary approaches to the study of consciousness
    - Network mechanisms of consciousness and unconsciousness
    -Theories of consciousness
    - Interfaces of sleep neurobiology and general anesthesia
    - Intraoperative awareness and metrics of consciousness

    Recent Publications See All Publications
    • Preprint
      Psilocybin induces dose-dependent changes in functional network organization in rat cortex.
      Silverstein BH, Kolbman N, Nelson A, Liu T, Guzzo P, Gilligan J, Lee U, Mashour GA, Vanini G, Pal D. 2024 Feb 15; DOI:10.1101/2024.02.09.579718
      PMID: 38405722
    • Journal Article
      Ketamine and the paradox of anaesthetic state transitions.
      Mashour GA. Br J Anaesth, 2024 Feb; 132 (2): 224 - 226. DOI:10.1016/j.bja.2023.11.030
      PMID: 38092601
    • Journal Article
      Urethane anaesthesia exhibits neurophysiological correlates of unconsciousness and is distinct from sleep.
      Mondino A, González J, Li D, Mateos D, Osorio L, Cavelli M, Castro-Nin JP, Serantes D, Costa A, Vanini G, Mashour GA, Torterolo P. Eur J Neurosci, 2024 Feb; 59 (4): 483 - 501. DOI:10.1111/ejn.15690
      PMID: 35545450
    • Preprint
      Propofol Disrupts the Functional Core-Matrix Architecture of the Thalamus in Humans.
      Huang Z, Mashour GA, Hudetz AG. 2024 Jan 24; DOI:10.1101/2024.01.23.576934
      PMID: 38328136
    • Journal Article
      Hormonal basis of sex differences in anesthetic sensitivity.
      Wasilczuk AZ, Rinehart C, Aggarwal A, Stone ME, Mashour GA, Avidan MS, Kelz MB, Proekt A, ReCCognition Study Group . Proc Natl Acad Sci U S A, 2024 Jan 16; 121 (3): e2312913120 DOI:10.1073/pnas.2312913120
      PMID: 38190526
    • Journal Article
      Intravenous psilocybin attenuates mechanical hypersensitivity in a rat model of chronic pain.
      Kolbman N, Liu T, Guzzo P, Gilligan J, Mashour GA, Vanini G, Pal D. Curr Biol, 2023 Dec 18; 33 (24): R1282 - R1283. DOI:10.1016/j.cub.2023.10.016
      PMID: 38113836
    • Journal Article
      Functional geometry of the cortex encodes dimensions of consciousness.
      Huang Z, Mashour GA, Hudetz AG. Nat Commun, 2023 Jan 5; 14 (1): 72 DOI:10.1038/s41467-022-35764-7
      PMID: 36604428
    • Journal Article
      Psychedelic concentrations of nitrous oxide reduce functional differentiation in frontoparietal and somatomotor cortical networks.
      Dai R, Huang Z, Larkin TE, Tarnal V, Picton P, Vlisides PE, Janke E, McKinney A, Hudetz AG, Harris RE, Mashour GA. Commun Biol, 2023 Dec 19; 6 (1): 1284 DOI:10.1038/s42003-023-05678-1
      PMID: 38114805
    Featured News & Stories 88% Reduction in GHG Emissions
    Department News
    Green Anesthesia Initiative exceeds lofty goals for reduction in emissions
    The Department of Anesthesiology’s Green Anesthesia Initiative (GAIA) has taken an ambitious approach to environmental sustainability resulting in an 88% reduction of inhaled anesthetic greenhouse gas emissions.
    Department News
    George Mashour, MD, PhD, featured on the StarTalk Podcast
    George Mashour, MD, PhD at the University of Michigan Department of Anesthesiology featured on the StarTalk Podcast.
    Department News
    Green Anesthesia Initiative quickly shows progress
    Is there a common path to the psychedelic experience?
         Research By the Numbers FY22.jpg
    Department News
    U-M Anesthesiology ranked #1 in NIH funding for eighth consecutive year with more than $22M in funding
    Three researchers — Drs. George Mashour, Chad Brummett, and David Williams — ranked in top 7 for PI funding.
    Department News
    Department of Anesthesiology launches initiative to minimize the field’s impact on climate change
    The initiative aims to reduce the Department of Anesthesiology's greenhouse gas emissions from anesthetic gases by 80%.