Brian Ross, Ph.D.

Roger A. Berg Radiology Research Professor
Professor, Radiology
Professor, Biological Chemistry

2071 BSRB

109 Zina Pitcher Place

Ann Arbor, MI  48109-2200

 

(734) 763-2099

Areas of Interest

Molecular imaging is as an exciting area of multidisciplinary research that allows physiology and molecular processes to be visualized in living tissue. Instrumentation involved in molecular imaging includes magnetic resonance imaging (MRI), bioluminescence imaging (BLI), positron emission tomography (PET) and x-ray computer assisted tomography (CT). As part of the Center for Molecular Imaging, we are developing applications for imaging to allow for investigations of cancer growth and response to therapy including noninvasive detection of molecular signaling events in living tissue. Translation of developed algorithms into the clinical setting are ongoing.

Honors & Awards

2015   Editor-in-Chief, Tomography
2014   Outstanding Teacher Award, International Society for Magnetic Resonance in Medicine
2013   Distinguished Investigator Award, Academy of Radiology Research
2012   Roger A. Berg Professorship, University of Michigan
2011   Outstanding Teacher Award, International Society for Magnetic Resonance in Medicine
2009   Elected Fellow, International Society for Magnetic Resonance in Medicine
2007   Scientific Advisory Board, Cancer Research UK Cambridge Research Institute
2005   Elected President, Society for Molecular Imaging
2004   Chandran Lectureship, Duke University
2004   Member, Advisory Panel of the American College of Radiology Imaging Network
2002   Executive Editor, Molecular Imaging
2001   Elected Treasurer, Society for Molecular Imaging
1998   Founding Editor, Neoplasia
1987   Research Fellow, Association for Brain Tumor Research

Published Articles or Reviews

Recent Publications

Three-Dimensional Growth Analysis of Thoracic Aortic Aneurysm With Vascular Deformation Mapping.
Burris NS, Hoff BA, Patel HJ, Kazerooni EA, Ross BD.
Circ Cardiovasc Imaging. 2018; 11: e008045.

Multimodal imaging provides insight into targeted therapy response in metastatic prostate cancer to the bone.
Hoff BA, Brisset JC, Galbán S, Van Dort M, Smith DC, Reichert ZR, Jacobson JA, Luker GD, Chenevert TL, Ross BD.
Am J Nucl Med Mol Imaging. 2018; 8: 189-99.

Ocular Toxicity Profile of ST-162 and ST-168 as Novel Bifunctional MEK/PI3K Inhibitors.
Smith A, Pawar M, Van Dort ME, Galbán S, Welton AR, Thurber GM, Ross BD, Besirli CG.
J Ocul Pharmacol Ther. 2018; 34: 477-85.

Structure-Guided Design and Initial Studies of a Bifunctional MEK/PI3K Inhibitor (ST-168).
Van Dort ME, Galbán S, Nino CA, Hong H, Apfelbaum AA, Luker GD, Thurber GM, Atangcho L, Besirli CG, Ross BD.
ACS Med Chem Lett. 2017; 8: 808-13.

A Bifunctional MAPK/PI3K Antagonist for Inhibition of Tumor Growth and Metastasis.
Galbán S, Apfelbaum AA, Espinoza C, Heist K, Haley H, Bedi K, Ljungman M, Galbán CJ, Luker GD, Dort MV, Ross BD.
Mol Cancer Ther. 2017; 16: 2340-50.

MRI-Guided Stereotactic Biopsy of Murine GBM for Spatiotemporal Molecular Genomic Assessment.
Galbán S, Al-Holou WN, Wang H, Welton AR, Heist K, Hu XK, Verhaak RG, Zhu Y, Espinoza C, Chenevert TL, Hoff BA, Galbán CJ, Ross BD.
Tomography. 2017; 3: 9-15.

Quantitative and Dynamic Imaging of ATM Kinase Activity by Bioluminescence Imaging.
Nyati S, Young G, Ross BD, Rehemtulla A.
Methods Mol Biol. 2017; 1599: 97-111.

For a list of publications from MyNCBI, click HERE