David Aminoff, Ph.D., D.Sc.

Professor Emeritus, Biological Chemistry

Ofc: 4303 MSRB III
1150 W. Medical Center Drive
Ann Arbor, MI 48109-5606

 

(734) 764-2591

Areas of Interest

Role of sialoglyconjugates in health, disease and aging. Preparation of the Universal Blood Donor type. The physiological signal for clearance of senescent red blood cells from the circulation. Currently we are working on establishing Red Blood Cells as a time capsule, a new paradigm in blood analysis, capable of providing valuable history of 4 months prior to the date of the blood draw.  

Honors & Awards

Postdoctoral Sabbatical Award, Department of Biophysics, Weizmann Institute of Science, Israel, 1973
Postdoctoral Sabbatical Award, Department of Biochemistry, College of Physicians and Surgeons, Columbia University, 1955–1956
First Class Honors–B.Sc. in Chemistry, 1945
Alleyn Exhibition, 1943

Published Articles or Reviews

Selected Publications

Research into selective biomarkers of erythrocyte exposure to organophosphorus compounds.
Aminoff D, Bochar DA, Fuller AA, Mapp AK, Showalter HD, Kirchhoff PD.
Anal Biochem. 2009; 392: 155–61.

Cellular and molecular mechanisms of senescent erythrocyte phagocytosis by macrophages. A review.
Bratosin D, Mazurier J, Tissier JP, Estaquier J, Huart JJ, Ameisen JC, Aminoff D, Montreuil J.
Biochimie. 1998; 80: 173–95.

Molecular biomarkers of aging: the red cell as a model.
Aminoff D, Rolfes-Curl A, Supina E.
Arch Gerontol Geriatr. 1992; 15 Suppl 1: 7–15.

Flow cytometric analysis of human erythrocytes: II. Possible identification of senescent RBC with fluorescently labelled wheat germ agglutinin.
Rolfes-Curl A, Ogden LL, Omann GM, Aminoff D.
Exp Gerontol. 1991; 26: 327–45.

Flow cytometric analysis of human erythrocytes: I. Probed with lectins and immunoglobulins.
Gutowski KA, Hudson JL, Aminoff D.
Exp Gerontol. 1991; 26: 315–26.

For a list of publications from Michigan Research Experts, click HERE