Areas of Interest
Role of sialoglyconjugates in health, disease and aging. Preparation of the Universal Blood Donor type. The physiological signal for clearance of senescent red blood cells from the circulation. Currently we are working on establishing Red Blood Cells as a time capsule, a new paradigm in blood analysis, capable of providing valuable history of 4 months prior to the date of the blood draw.
Honors & Awards
1973 Postdoctoral Sabbatical Award; Department of Biophysics, Weizmann Institute of Science, Israel
1955-56 Postdoctoral Sabbatical Award: College of Physicians and Surgeons, Department of Biochemistry, Columbia University
1945 First Class Honors-B.Sc. in Chemistry
1943 Alleyn Exhibition
Research into selective biomarkers of erythrocyte exposure to organophosphorus compounds.
Aminoff D, Bochar DA, Fuller AA, Mapp AK, Showalter HD, Kirchhoff PD.
Anal Biochem. 2009; 392: 155-61.
Cellular and molecular mechanisms of senescent erythrocyte phagocytosis by macrophages. A review.
Bratosin D, Mazurier J, Tissier JP, Estaquier J, Huart JJ, Ameisen JC, Aminoff D, Montreuil J.
Biochimie. 1998; 80: 173-95.
Molecular biomarkers of aging: the red cell as a model.
Aminoff D, Rolfes-Curl A, Supina E.
Arch Gerontol Geriatr. 1992; 15 Suppl 1:7-15.
Flow cytometric analysis of human erythrocytes: II. Possible identification of senescent RBC with fluorescently labelled wheat germ agglutinin.
Rolfes-Curl A, Ogden LL, Omann GM, Aminoff D.
Exp Gerontol. 1991; 26: 327-45.
Flow cytometric analysis of human erythrocytes: I. Probed with lectins and immunoglobulins.
Gutowski KA, Hudson JL, Aminoff D.
Exp Gerontol. 1991; 26: 315-26.
For a list of publications from Michigan Research Experts, click HERE