Kaushik Ragunathan, Ph.D.

Assistant Professor, Biological Chemistry

Ofc: 3220D MSRB III

Lab: 3240 MSRB III

1150 W. Medical Center Drive

Ann Arbor, MI 48109-5606

 

(734) 763-0641

Appointments

Biological Chemistry, Medical School

Areas of Interest

My lab is interested in the molecular mechanisms that define how the combinatorial logic of histone modifications and its dynamic interactions with histone binding proteins encodes stable and heritable patterns of gene expression. We take a multidisciplinary perspective that synthesizes genetics, biochemistry and biophysical approaches to capture cellular processes across different spatial and temporal regimes.  

Credentials

Postdoctoral fellow, Department of Cell Biology, Harvard Medical School
Ph.D, Biophysics and Computational Biology, University of Illinois, Urbana-Champaign
B.Tech, Biotechnology, PSG College of Technology, India

Published Articles or Reviews

Evolution of protein-coupled RNA dynamics during hierarchical assembly of ribosomal complexes.
Abeysirigunawardena SC, Kim H, Lai J, Ragunathan K, Rappé MC, Luthey-Schulten Z, Ha T, Woodson SA.
Nat Commun. 2017; 8: 492.

Epigenetics. Epigenetic inheritance uncoupled from sequence-specific recruitment.
Ragunathan K, Jih G, Moazed D.
Science. 2015; 348: 1258699.

Cooperative conformational transitions keep RecA filament active during ATPase cycle.
Kim SH, Ragunathan K, Park J, Joo C, Kim D, Ha T.
J Am Chem Soc. 2014; 136: 14796-800.

Protein-guided RNA dynamics during early ribosome assembly.
Kim H, Abeysirigunawarden SC, Chen K, Mayerle M, Ragunathan K, Luthey-Schulten Z, Ha T, Woodson SA.
Nature. 2014; 506: 334-8.

ATP-independent diffusion of double-stranded RNA binding proteins.
Koh HR, Kidwell MA, Ragunathan K, Doudna JA, Myong S.
Proc Natl Acad Sci USA. 2013; 110: 151-6.

RecA filament sliding on DNA facilitates homology search.
Ragunathan K, Liu C, Ha T.
Elife. 2012; 1: e00067.

Real-time observation of strand exchange reaction with high spatiotemporal resolution.
Ragunathan K, Joo C, Ha T.
Structure. 2011; 19: 1064-73.

For a list of publications from Pubmed, click HERE

Web Sites