June 19, 2018

Elizabeth Abshire and Jennifer Bohn Co-author article in Nucleic Acids Research

The structure of human Nocturnin reveals a conserved ribonuclease domain that represses target transcript translation and abundance in cells.

Elizabeth Abshire and Jennifer Bohn have co-authored an article describing the crystal structure and translational repression activity of human Nocturnin, a circadian rhythm-regulated ribonuclease that has been implicated in governing lipid metabolism, adipogenesis, and skeletal development. These studies represent a collaboration among the Trievel, Goldstrohm, and Freddolino laboratories and have been published in Nucleic Acids Research.

Read the article HERE