September 23, 2019

Janet Smith and David Sherman labs publish a paper in Nature Chemistry

Fungal indole alkaloid biogenesis through evolution of a bifunctional reductase/Diels-Alderase

Researchers in the Smith and Sherman labs and their collaborators revealed the process fungi use to build a large class of bioactive chemical compounds called prenylated indole alkaloids, and discovered a chemical reaction that is nearly unprecedented in nature. Their study has been published in Nature Chemistry.