Ryan Baldridge, Ph.D.
Mechanisms of membrane-bound protein quality control systems
Ruma Banerjee, Ph.D.
Chemical biology of hydrogen sulfide signaling; regulation of mammalian sulfur metabolism in health and disease; structural enzymology of human B12 trafficking proteins
Jay Brito Querido, Ph.D.
Single-particle cryo-electron microscopy in combination with biochemical approaches to study how messenger RNA translation is regulated in human health and disease
Uhn-Soo Cho, Ph.D.
Biochemical and structural studies of kinetochore assembly, histone chaperones, and Sestrin-mediated mTORC1 regulation
Michael Cianfrocco, Ph.D.
Structural biology and biophysics underlying microtubule-based intracellular transport
Peter Freddolino, Ph.D.
Bacterial chromosomal structure and its effect on gene regulation; structure-function relationships in transcriptional regulators; merging experimental and computational data in protein-DNA and protein-RNA binding free energy landscapes; high throughput structure-based function prediction; optimal use of crosslinking mass spectrometry for structure determination; structural genomics
Tobias Giessen, Ph.D.
Structure, function, and engineering of large protein assemblies
Daniel Goldman, Ph.D.
Identification of signaling pathways, chromatin alterations, and gene expression programs that drive central nervous system regeneration using the retina as a model system
Phyllis Hanson, M.D., Ph.D.
Protein-protein and protein-membrane interactions involved in membrane trafficking and organelle structure
Tom Kerppola, Ph.D.
Protein interactions and modifications in living cells and animals; roles of transcription factor complexes in the control of gene expression; mechanisms whereby cells and animals recognize and respond to synthetic chemicals
James Morrissey, Ph.D.
Biochemistry of the human blood clotting system; structural studies of protein-membrane complexes
Ruthann Nichols, Ph.D.
Structure-activity relationship and signaling pathways of neuropeptides and receptors of the RFamide peptide family and their role in regulating heart rate and muscle contractions
Rachel Niederer, Ph.D.
Combining high-throughput experimental methods with biochemistry and molecular biology to discover translational control elements and characterize novel regulatory mechanisms impacting gene expression