Ursula Jakob, Ph.D.

Patricia S. Yaeger Collegiate Professor, Molecular, Cellular, and Developmental Biology
Professor, Biological Chemistry

5014 BSB

1105 N. University Avenue

Ann Arbor, MI  48109-1085


(734) 615-1286

Areas of Interest

Biochemical aspects of the bacterial response to oxidative stress.

Honors & Awards

2001  Biological Sciences Scholar, University of Michigan
2000  Career Award in the Biomedical Sciences, Burroughs Wellcome Fund
1998  Sokol Postdoctoral Award

Published Articles or Reviews

Recent Publications

Chaperone activation and client binding of a 2-cysteine peroxiredoxin.
Teixeira F, Tse E, Castro H, Makepeace KAT, Meinen BA, Borchers CH, Poole LB, Bardwell JC, Tomás AM, Southworth DR, Jakob U.
Nat Commun. 2019; 10: 659.

Inorganic polyphosphate, a multifunctional polyanionic protein scaffold.
Xie L, Jakob U.
J Biol Chem. 2019; 294: 2180-90.

Polyphosphate Stabilizes Protein Unfolding Intermediates as Soluble Amyloid-like Oligomers.
Yoo NG, Dogra S, Meinen BA, Tse E, Haefliger J, Southworth DR, Gray MJ, Dahl JU, Jakob U.
J Mol Biol. 2018; 430: 4195-208.

Phase shifts in protein folding space: links to stress adaptation and disease.
Alberti S, Jakob U.
Mol Biol Cell. 2018; 29: 695.

Maintaining a Healthy Proteome during Oxidative Stress.
Reichmann D, Voth W, Jakob U.
Mol Cell. 2018; 69: 203-13.

Do developmental temperatures affect redox level and lifespan in C. elegans through upregulation of peroxiredoxin?
Henderson D, Huebner C, Markowitz M, Taube N, Harvanek ZM, Jakob U, Knoefler D.
Redox Biol. 2018; 14: 386-90.

Stress-Activated Chaperones: A First Line of Defense.
Voth W, Jakob U.
Trends Biochem Sci. 2017; 42: 899-913.

Pseudomonas aeruginosa defense systems against microbicidal oxidants.
Groitl B, Dahl JU, Schroeder JW, Jakob U.
Mol Microbiol. 2017; 106: 335-50.

For a list of publications from PubMed, click HERE

Web Sites