Amanda Pacheco

I graduated from Bridgewater State University in Bridgewater, MA in 2019 with a B.S. in Biology. During my undergrad, I studied the cross-talk between apoptosis and autophagy in cervical cancer cells and was a summer intern at Pfizer in the department of bio-medicine design. I'm currently a member of Dr. Howard Crawford's lab where I study cellular plasticity and tuft cells in pancreatic cancer. I am fluent in Portuguese and in my free time I enjoy reading, painting, cooking, and playing with my two ferrets.

My research studies the role of Pou2f3, a transcription factor involved in tuft cell biology. Pou2f3 and tuft cells are highly understudied but have recently been implicated in some cancers. We aim to expand research in this area by investigating the role of Pou2f3 and tuft cells in pancreatic cancer.

Cell culture, conditional knockout mouse models, immunofluorescence, immunohistochemistry, organoids

First Generation College Student