Aylin graduated from the University of California - Los Angeles with a B.S. in Molecular, Cell, and Developmental Biology and a minor in French Language and Culture in June 2021. While at UCLA, she studied the metabolic plasticity of pre-implantation mouse embryos and the importance of Pyruvate Kinase during periods of metabolic stress and pyruvate deficiency under Dr. Utpal Banerjee. In July 2021, she moved to Boston, Massachusetts and studied the role of antioxidants in BRCA1/P53 loss driven breast cancer using a genetically engineered mouse model using multiplex immunofluorescence and spatial analysis; she also studied integrin expression and drug resistance in human triple negative breast cancer cell lines in Dr. Joan Brugge's lab at Harvard Medical School. In 2023, she joined the PIBS program with a strong interest in Cancer Biology! In her free time, Aylin loves reading fiction, drinking coffee, board games, gardening, cooking, and travelling!
Biography
Research Interests
I am interested in the metabolic characterization of liver metastases in pancreatic cancer, as well as the effects of chemotherapy on the tumor microenvironment in patients and how these effects can drive treatment resistance and tumor recurrence.
Techniques Used
Multiplex immunofluorescence, western blotting, cell and tissue culture techniques, Mouse Husbandry/Injection techniques
Abstracts
Aylin Z Henstridge; Padma Kadiyala; Ahmed M Elhossiny; Jianhua Liu; Vaibhav Sahai; Nicole Peterson; Jorge Machicado; Richard Kwon; Allison Schulman; Erik Wamsteker; George Philips; Martin Fernandez-Zapico; Mark Truty; Costas Lyssiotis; Timothy Frankel; Filip Bednar; Marina Pasca di Magliano; Eileen S Carpenter, Abstract A062: Neurotropic fibroblast population increases following exposure to chemotherapy in pancreatic adenocarcinoma ,AACR Advanced in Pancreatic Research, Boston MA, September 2024. https://doi.org/10.1158/1538-7445.PANCREATIC24-A062
Awards
GM150581 T32 Systems and Integrative Physiology Training Grant Awardee, Rackham Pre Candidate Award
Publications
Student Roles
Cancer Biology Social Co-Chair, 2024
Cancer Bio Mentor
Costas Lyssiotis, Ph.D.
