Donald Little

Donald Little

Graduate Student

Biography

I received my Bachelor of Science degree in Genetics and a minor in Wildlife Science from Purdue University in 2015. During my undergraduate career, I was involved in honors research, teaching, and mentoring. I also completed a Summer Scholars research project at the Stowers Institute for Medical Research in 2014. After graduation, I joined the UM Cancer Biology Graduate Program as a Rackham Merit Fellow and began my thesis work in Dr. Gary Hammer's lab. Outside of lab, I enjoy hiking, traveling, and playing basketball.

Research Interests

My project focuses on the role of WNT signaling in adrenal development and homeostasis. WNT signaling plays a crucial role in adrenal biology and is perturbed in a high number of adrenal cancer cases, but the molecular mechanisms involved are not fully understood. Specifically, I am using various mouse models and in vitro single cell techniques to study the effect of WNT2B on adrenocortical progenitor cell maintenance and its potential role in adrenal cancer.