Margaret V. Westfall, Ph.D.

Margaret V. Westfall, Ph.D.

Associate Professor of Cardiac Surgery
Associate Professor of Molecular and Integrative Physiology

Biography

Margaret Westfall's training is in integrated organ systems and cellular physiology/biophysics and her expertise is in cardiac physiology. Research in Westfall's lab is focused on understanding cardiac function and heart failure. Current studies in the lab are focused on PKC signaling modulation of troponin I, a sarcomeric molecular switch protein. This work involves basic physiological responses and the alterations in function observed with the development of heart failure. A significant component of her lab's work on troponin I relies on structural and functional measurements made in individual terminally-differentiated adult cardiac myocytes isolated from a variety of species, including failing human hearts. Another focus of the lab is investigating the cardiac proteome and the remodeling process during human heart failure.

Education

  • 1978 – Colorado College, Colorado Springs, CO, BA, Biology
  • 1981 – University of Montana, Missoula, MT, MS, Microbiology
  • 1989 – Loyola University, Maywood, IL, PhD, Physiology
  • 1989-1993 – University of Illinois - Chicago, Chicago, IL, Physiology
  • 1993-1997 – University of Michigan, Ann Arbor, MI, Physiology

Honors & Awards

Positions and Employment

  • 1997-2000 – Assistant Research Scientist, Dept. of Physiology, University of Michigan
  • 1999-2008 – Assistant Professor, Department of Molecular and Integrative Physiology, UM
  • 2000-2008 – Assistant Professor, Dept. of Surgery, Cardiac Surgery Section, UM
  • 2008-2012 – Associate Professor, Dept. of Surgery, Cardiac Surgery Section, UM
  • 2008-Present – Associate Professor, Dept. of Molecular and Integrative Physiology, UM
  • 2009-Present – Assistant Professor, Dept. of Biomedical Engineering, UM
  • 2012-Present – Associate Professor, Dept. of Cardiac Surgery, UM

Other Experience and Professional Activities:

  • 1998-2000 – American Heart Association ÐMichigan: Student Fellowships
  • 2001-2004 – American Heart Association Study Section: Cellular Cardiovascular Physiology and Pharmacology Study Group
  • 10/2004; 4/2005 – NIH PPG Special Review Committee
  • 03/2006; 11/2013 – NIH Ad hoc reviewer
  • 11/2006; 3/2007; 11/2007; 3/2008; 10/2008; 4/2009; 05/2009; 5/2011, 5/2012; 11/2013 – NIH ZRG1 CVS Special Review Committee
  • 06/2009-06/2010 – NIH CCHF Ad hoc reviewer
  • 07/2010-06/2014 – NIH CCHF Member
  • 2008-present – Editorial Board: American Journal of Physiology Heart and Circulatory Physiology: 2007-present; Journal of Molecular and Cellular Cardiology:

Honors

  • 1996-97 – Basic Science Fellowship
  • 1996-98 – Schmitt Dissertation Fellowship
  • 1996-97 – National Research Service Award, NIH Grant HL-05059
  • 1992 – Travel Grant, International Society for Heart Research 14th World Congress
  • 1993 – Upjohn Young Investigator Finalist, Intl. Society for Heart Research

Credentials

Certification and Licensure

  • 1972    National Board of Medical Examiners
  • 1973    State of Michigan
  • 1978    American Board of Surgery
  • 1980    American Board of Thoracic Surgery
  • 1980    State of New York
  • 1997    State of Ohio