Nathaniel Parchment, MD

Integrated Thoracic Surgery Residency


Nate was born and raised in Maryland. He attended undergrad at Clemson University, where he majored in Bioengineering with a focus in Biomaterials. During his time at Clemson, he worked in the lab of Dr Naren Vyavahare developing novel tissue fixation protocols for porcine and bovine bioprosthetic heart valves. He spent his undergraduate summers at the National Cancer Institute in the lab of Dr Bradley St Croix developing novel, targeted oncologic therapies through antibody drug conjugates, specifically targeting tumor endothelium. He then completed his medical degree at the University of Maryland School of Medicine, where he worked in the lab of Dr Sunjay Kaushal, investigating novel, acellular regenerative therapies for use in hypoplastic left heart syndrome. He then began his residency in cardiothoracic surgery at the University of Michigan. His research interests include the development of novel therapeutic devices and targeted medications for the improvement of cardiovascular care, particularly in the realm of cardiothoracic transplantation and mechanical circulatory support.

Why did you choose to train at University of Michigan?
While I have a strong interest in cardiothoracic transplantation, I sought a training program that would provide excellent training in all three realms of cardiothoracic surgery – adult cardiac, general thoracic, and congenital cardiac surgery. The University of Michigan provides this through an unmatched cohort of faculty who are committed to excellent training throughout residency. The University of Michigan also provides innumerable opportunities for research collaboration and support with top notch research faculty and institutional support.

What are your hobbies?
I am a college football enthusiast which makes falls in Ann Arbor fantastic. I also am an avid golfer and enjoy the numerous courses in the Ann Arbor area.

Areas of Interest

Research Interest
During my academic development time, I will be working with Dr Andrea Obi in the Section of Vascular Surgery on elucidating the underlying mechanism responsible for COVID coagulopathy. Through this project, we plan to test a novel, targeted venous thromboembolic prophylaxis aimed to prevent VTE in sepsis while minimizing bleeding complications. Ultimately, I hope to extend the expertise I develop in the areas of coagulopathy and immunology to examine the role of the inflammatory response during cardiopulmonary bypass and mechanical circulatory support in the associated coagulopathy in hopes of developing targeted anticoagulants with minimal bleeding risks.

During academic development time, I received funding and support initially from the Vascular Surgery Departmental T-32, then was awarded a two-year individual NHLBI F-32 grant. I also received support through selection as a Frederick Coller Research Fellow.


2020: University of Maryland, School of Medicine, MD

2016: Clemson University, Bioengineering, BS

Published Articles or Reviews

Bittle GJ, Morales D, Pietris N, Parchment N, Parsell D, Peck K, Deatrick KB, Rodriguez-Borlado L, Smith RR, Marbán L, Kaushal S. Exosomes isolated from human cardiosphere-derived cells attenuate pressure overload-induced right ventricular dysfunction. J Thorac Cardiovasc Surg. 2021 Sep;162(3):975-986.e6. PMID: 33046229.

Parchment N, Brescia AA, Ailawadi G. Commentary: Back to the future: Failed mitral valve bioprosthesis in the setting of mitral annular calcification. JTCVS Tech. 2021 Aug 6;10:269-270. PMID: 34977735.

Ambastha C, Bittle GJ, Morales D, Parchment N, Saha P, Mishra R, Sharma S, Vasilenko A, Gunasekaran M, Al-Suqi MT, Li D, Yang P, Kaushal S. Regenerative medicine therapy for single ventricle congenital heart disease. Transl Pediatr. 2018 Apr;7(2):176-187. PMID: 29770299.

 A complete list of published work can be found by clicking this PubMed link.