Areas of Interest
Our laboratory currently focusses on three different areas of hematopoiesis. We are investigating how transcription factors GATA2 and GATA3 regulate hematopoietic stem cell function and maintenance, how T cells develop in the thymus, and how specific enzymatic inhibitors inactivate epigenetic modifying enzymes in erythroid progenitors leading to induced synthesis of fetal hemoglobin as a treatment for sickle cell disease and beta-thalassemia, the world's most common inherited diseases.
Associated Grad Programs
Cell & Developmental Biology, Cellular & Molecular Biology
- California Institute of Technology, Postdoctoral Fellowship, 09/1978
- Institute of Molecular Biology University of Oregon, Ph.D., 04/1975
University of California-San Diego, B.A., 06/1970