Doug Engel

Doug Engel

Professor
Research Focus: hematopoiesis, erythropoiesis, T cell development, hematopoietic stem cells, transcription

3035 BSRB 
109 Zina Pitcher Place
Ann Arbor MI 48109-2200

734-615-7509

Areas of Interest

Our laboratory currently focusses on three different areas of hematopoiesis. We are investigating how transcription factors GATA2 and GATA3 regulate hematopoietic stem cell function and maintenance, how T cells develop in the thymus, and how specific enzymatic inhibitors inactivate epigenetic modifying enzymes in erythroid progenitors leading to induced synthesis of fetal hemoglobin as a treatment for sickle cell disease and beta-thalassemia, the world's most common inherited diseases. 

Associated Grad Programs

Cell & Developmental Biology, Cellular & Molecular Biology

Credentials

  • California Institute of Technology, Postdoctoral Fellowship, 09/1978 
  • Institute of Molecular Biology University of Oregon, Ph.D., 04/1975
  • University of California-San Diego, B.A., 06/1970

     

Published Articles or Reviews