Areas of Interest
Human pluripotent stem cells, grown in a culture dish, can allow study of human development and disease. Organoid-like structures grown from such cells recapitulate several tissues, including colon, small intestine, esophagus and lung. Using these, we can ask: How do organs assemble into functional units? What are the genes and signaling programs necessary to form proper organs and which of these are functioning improperly in disease?