Kristen Verhey

A. Kent Christensen Collegiate Professor
Research Focus: Intracellular Trafficking, Microtubules, Motor proteins, Cilia, Axonal transport, Posttranslational Modifications

3041 BSRB 
109 Zina Pitcher Place
Ann Arbor, MI 48109-2200

734-615-7787

Areas of Interest

Inside every cell, motor proteins move diverse cargos over a set of highly connected "railroad tracks"composed of microtubules. How do motors choose the proper cargo? How do they generate force and directed motion?  How do they choose tracks that lead to specific cellular destinations such as the growth cone of an axon?

Associated Grad Programs

Cell & Developmental Biology, Cellular & Molecular BiologyBiophyics

Featured Publications

Engelke MF, Winding M, Yue Y, Shastry S, Teloni F, Reddy S, Blasius TL, Soppina P, Hancock WO,Gelfand VI, and Verhey KJ.  (2016).  Engineered kinesin motor proteins amenable to small molecule inhibition. Nature Communications 7:11159.  PMCID: PMC4822052

Norris SR, Soppina V, Dizaji AS, Schimert KI, Sept D, Cai D, Sivaramakrishnan S, and Verhey KJ.  (2014).A method for multiprotein assembly in cells reveals independent action of kinesins in complex.  Journal ofCell Biology 207(3): 393-406.  PMCID: PMC4226728

Takao D, Dishinger JF, Kee HL, Pinskey JM, Allen BL, and Verhey KJ.  (2014).  An assay for clogging the ciliary pore complex distinguishes mechanisms of cytosolic and membrane protein entry.  Current Biology. 24(19): 2288-2294. PMCID: PMC4189977

Kee HL, Dishinger JF, Blasius TL, Liu CJ, Margolis B, and Verhey KJ.  (2012).  A size-exclusion barrier and nucleoporins characterize a ciliary pore complex that regulates transport into cilia.  Nature Cell Biology14(4): 431-437. PMCID: PMC3319646

Cai D, McEwen D, Martens JR, Meyhofer E, and Verhey KJ.  (2009).  Single Molecule Imaging RevealsDifferences in Microtubule Track Selection by Kinesin Motors.  PLoS Biology 7: e1000216.  PMCID:PMC2749942.

 

Credentials

  • Harvard Medical School, Postdoctoral, 07/2002
  • Harvard University, Ph.D., 05/1995
  • University of Michigan, B.S., 05/1987 
     

     

 

Published Articles or Reviews

Web Sites