Areas of Interest
Inside every cell, motor proteins move diverse cargos over a set of highly connected "railroad tracks"composed of microtubules. How do motors choose the proper cargo? How do they generate force and directed motion? How do they choose tracks that lead to specific cellular destinations such as the growth cone of an axon?
Associated Grad Programs
Engelke MF, Winding M, Yue Y, Shastry S, Teloni F, Reddy S, Blasius TL, Soppina P, Hancock WO,Gelfand VI, and Verhey KJ. (2016). Engineered kinesin motor proteins amenable to small molecule inhibition. Nature Communications 7:11159. PMCID: PMC4822052
Norris SR, Soppina V, Dizaji AS, Schimert KI, Sept D, Cai D, Sivaramakrishnan S, and Verhey KJ. (2014).A method for multiprotein assembly in cells reveals independent action of kinesins in complex. Journal ofCell Biology 207(3): 393-406. PMCID: PMC4226728
Takao D, Dishinger JF, Kee HL, Pinskey JM, Allen BL, and Verhey KJ. (2014). An assay for clogging the ciliary pore complex distinguishes mechanisms of cytosolic and membrane protein entry. Current Biology. 24(19): 2288-2294. PMCID: PMC4189977
Kee HL, Dishinger JF, Blasius TL, Liu CJ, Margolis B, and Verhey KJ. (2012). A size-exclusion barrier and nucleoporins characterize a ciliary pore complex that regulates transport into cilia. Nature Cell Biology14(4): 431-437. PMCID: PMC3319646
Cai D, McEwen D, Martens JR, Meyhofer E, and Verhey KJ. (2009). Single Molecule Imaging RevealsDifferences in Microtubule Track Selection by Kinesin Motors. PLoS Biology 7: e1000216. PMCID:PMC2749942.
- Harvard Medical School, Postdoctoral, 07/2002
- Harvard University, Ph.D., 05/1995
- University of Michigan, B.S., 05/1987