The mission of the Center for Cell Plasticity and Organ Design is to unite interdisciplinary research efforts towards understanding the basic mechanisms by which organs and tissues are formed and maintained and to use this knowledge to regenerate or create replacement tissues and organs, improve stem cell therapies and effective organ transplantation systems that will correct acquired and genetic human disease.
Cell Plasticity Organ Design
News

CPOD Faculty Publication Spotlight-Miller Lab
Chumki SA, van den Goor LM, Hall BN, Miller AL . Mol Biol Cell. 2022 Dec 1;33. p115RhoGEF activates RhoA to support tight junction maintenance and remodeling.

CPOD Faculty Publication Spotlight-Fu Lab
Zheng Y, Yan RZ, Sun S, Kobayashi M, Xiang L, Yang R, Goedel A, Kang Y, Xue X, Esfahani SN, Liu Y, Resto Irizarry AM, Wu W, Li Y, Ji W, Niu Y, Chien KR, Li T, Shioda T, Fu J. Cell Stem Cell. 2022 Sep 1;29(9):1402-1419.e8. Single-cell analysis of embryoids reveals lineage diversification

CPOD Faculty Publication Spotlight-Seo Lab
Ekaputri S, Choi EK, Sabelli M, Aring L, Green KJ, Chang J, Bao K, Choi HS, Iwase S, Kim J, Corradini E, Pietrangelo A, Burke MD, Seo YA. Proc Natl Acad Sci U S A. 2022 Jun 28;119(26) A small molecule redistributes iron in ferroportin-deficient mice and patient-derived primary macrophages