We are studying the molecular basis of neurological disorders using mouse models of epilepsy, movement and behavioral disorders. This work has enabled us to identify several human disease mutations.
The development of diabetic kidney disease and understanding the mechanisms underlying the role of growth hormone in the causation of certain chronic complications of type 1 diabetes mellitus.
Using cell lines and neuronal models to investigate molecular mechanisms of Ubiquilin-2 (UBQLN2) regulation in normal cellular function and ALS caused by UBQLN2 mutations.
Implicit Bias Training, Anti-Racism Training, Intercultural Training, Bystander Training, I am a Rackham Faculty Ally for Diversity and a previous Lead of the DEI Committee for my home department
Research Interests:
virus assembly; virus entry; protein trafficking; protein-RNA interaction; protein-membrane interaction