Keegan

Catherine Keegan, MD, PhD

Dept. Pediatrics-Genetics
Research Interests:
Use of mouse models to understand the mechanisms that lead to birth defects affecting caudal structures in humans, and understand the mechanisms which telomere dysfunction causes distinct phenotypes

The focus of the research in my laboratory is the use of mouse models 1) to understand the mechanisms that lead to birth defects affecting caudal structures in humans, and 2) to understand the mechanisms by which telomere dysfunction causes distinct phenotypes in humans. Prior work in my laboratory has focused on genetically characterizing spontaneous mouse mutants as a platform to understand how disruption of key cellular and developmental processes can lead to structural birth defects and other diseases in humans.