Research Interests
The overarching goal of the lab is to identify putative predictive genomic biomarkers for targeted therapies and understand primary and secondary resistance mechanisms for these therapies. The lab utilizes next-generation sequencing strategies for the development and analysis of genomics-driven medicine clinical trials (precision medicine) and genetic characterization of therapeutic resistance. The lab also specializes in using high-throughput functional screens to identify therapeutic targets and molecular strategies to advance for pre-clinical modeling in cell lines and patient-derived xenograft models.