Our laboratory aims to explore the physiological role of endoplasmic reticulum (ER) homeostasis (with a special focus on both UPR and ERAD) and inflammation in the context of human diseases. We use genetic, immunological, molecular and cellular tools and approaches to produce new insights into disease pathogenesis, and to bring a standard excellence to all that we do as an individual scientist and as a laboratory. We have made significant contribution in the fields of physiological ER homeostasis and inflammation in health and diseases. In the last 8 years, we have published over 40 papers, including several seminal discoveries published in top journals, including Nat Cell Biology, Cell Metabolism, Developmental Cell, PNAS, Cell Reports, Diabetes, Mol Biol Cell and J Biol Chem. Our past achievements have demonstrated our desire to think outside the box, take the risk and develop breakthrough science. Our diverse research experience and knowledge in several research areas (immunology, cell biology, physiology and gastroenterology), together with our determination and dedication to scientific research and discovery, have provided an exceptional opportunity to accomplish our scientific goals and to make significant contributions to the understanding of human health and disease.
In addition to research, I am a dedicated teacher and mentor. I have trained several graduate students and postdoctoral fellows over the years, many of whom are now holding industrial and academic positions. My graduate students have successfully competed for prestigious HHMI International Scholar and AHA Predoctoral Fellowships. Moreover, I strive to bring the latest development in metabolism to undergraduate and graduate students in the course “Nutrient Metabolism” with over 120 students every year at Cornell. In May of 2014, I received the SUNY Chancellor’s Award for Excellence in Teaching, a top award for the best teachers in the NY State.