Thursday, May 11, 2017

"Statistical methods and analysis to identify disease-related variants from genetics studies"

10:00 AM to 12:00 PM

Forum Hall, 4th Fl., Palmer Commons Bldg.

Thesis Defense by Sai Chen, Ph.D. Candidate

Adviser: Goncalo Abecasis 


Advances in genotyping technology have greatly revolutionized the methodology in genetics research. Due to the dramatically decreasing cost of genotyping, millions of variants have been discovered from population-scale data. The findings provide a new insight into the human genome, and are continuously shaping our understanding of the genetic basis for disease. In this dissertation, I focus on three topics related to discovering disease-related variants in genetics studies in the aspects of method development and dataset analysis.