Wednesday, April 7, 2021

CCMB Seminar: "Host and Virus Responses During COVID-19 Transmission in Marine Recruits"

4:00 PM

This seminar will be web stream only

CCMB Seminar Series – sponsored by DCMB
by Dr. Stuart Sealfon ( Professor-Neurology, Neuroscience, and Pharmacological Sciences at Icahn School of Medicine)


More than 3,000 new Marine recruits were studied prospectively during their initial Marine-mandated two-week quarantine and their subsequent basic training at Parris Island. The COVID Health Action Response for Marines (CHARM) studied completed 20,000 study visits and obtained more than 70,000 biosamples including pre- to post- SARS-CoV-2 infections in more than 1000 recruits. Serological, transcriptomic, and epigenetic analyses identify the response signature to SARS-CoV-2 infection in these largely asymptomatic young adults. Phylogenetic analysis and modeling provide insight into epidemiology and guidance for public health measures.

Research Topics

Addiction, Apoptosis/Cell Death, Basal Ganglia, Bioinformatics, Brain, Cellular Immunity, Cerebral Cortex, Mathematical and Computational Biology, Multiple Sclerosis, Neuro-degeneration/protection, Receptors, Reproductive Biology, Signal Transduction, Theoretical Biology, Vaccine Development, Viruses and Virology