"Volumetric muscle loss (VML) is a clinically relevant problem for which current treatment methods are limited and are not 100% effective. Tissue-engineered skeletal muscle and commercially available hydrogels (HGs) are promising novel therapeutic options. This study aimed to access the biocompatibility of commercially available poly(ethylene glycol), methacrylated gelatin, and hyaluronic acid HGs in combination with our tissue-engineered skeletal muscle units to treat VML in a clinically relevant large animal model (sheep) after a 6-week recovery."
Pictured from left to right: Eileen Su, B.S. (Research Associate, Molecular and Integrative Physiology, University of Michigan) and Dr. Lisa Larkin, Ph.D. (Professor, Molecular and Integrative Physiology, University of Michigan)