A histologic image (H&E) showing in situ regenerated marrow-containing bone using new porous 3D scaffolds with synthetic peptides on nanofibers to activate cell-surface receptors.
"We are very excited about the discoveries reported in our recent publication and believe what we have created can transform bone grafts down the road for the millions of people who require them. What we invented are biodegradable polymer templates that contain peptides on nanofibers, acting like keys to open new gates to liberate the locked bone regeneration potentials from recipient's own cells. After the regeneration of pre-designed 3D bone tissue, the materials will degrade and disappear without potential long-term complications."
Pictured from left to right: Tongqing Zhou, Ph.D. Candidate (Macromolecular Science and Engineering Center, University of Michigan) and Dr. Peter Ma, Ph.D. (Professor, Biologic and Materials Sciences, University of Michigan)