CCMB Seminar Series

DCMB Seminar Series - Dr. Olga Troyanskaya
2019 Speaker: Olga Troyanskaya, Ph.D.

The CCMB Seminar Series (Sponsored by DCMB) is held at Palmer Commons, Forum Hall, each Wednesday, at 4:00 pm EST, on bioinformatics related topics. Each seminar is presented by an invited guest speaker. These seminars are live streamed and recorded and made available for future viewing via the DCMB YouTube Chanel.

Live Stream via Blue Jeans Events

Upcoming DCMB Events Calendar

Video Archive

2019 Seminar Video Archive

Oct 16, 2019

Oct 09, 2019

Oct 03, 2019

Apr 17, 2019

Apr 10, 2019

Mar 27, 2019

Mar 21, 2019

Feb 27, 2019

"Learning latent embeddings for genomic and proteomic data" -Dr. William Stafford Noble (University of Washington)

Feb 20, 2019

Feb 06, 2019

  • "Genetic Variation and 3D Genome Structure in Cancer" byDr. Feng Yue (Penn State Institute for Personalized Medicine)

Jan 23, 2019

  • 6th Annual Omenn Lecture:"Data-driven understanding of human disease: from AI to biological discoveries" - byDr. Olga Troyanskaya

Jan 09, 2019

  • "Origins of DNA Methylation Abnormalities in Cancer" - byDr. Peter Laird (Van Andel Research Institute)

2018 Seminar Video Archive

Dec 05, 2018

Nov 28, 2018

Nov 14, 2018

Nov 07, 2018

Oct 24, 2018

  • "Identifying transcription factor binding using open chromatin, transcriptome, and methylation data" - byDr. Michael Hoffman (University of Toronto)

Oct 10, 2018

Sep 26, 2018

Sep 19, 2018

  • "Developmental Modulation of Transcriptional Bursting During Organ of Corti Development" - by Dr. Joerg Waldhaus (UM)

Sep 12, 2018

  • "Decoding the Laws of Emergence and Self-Organization in Complex Collectives: Lessons Learned from Biological Systems" - by Dr. Paul Bogdan (USC)

Apr 18, 2018

Apr 11, 2018

  • "Combining machine learning and NMR spectroscopy to model invisible states of ribonucleic acids" - Dr. Aaron T. Frank, University of Michigan

Mar 28, 2018

  • "Functional 3D Chromosome and Genome Dynamics" - Dr. Peter Fraser, Professor, Department of Biological Science

Mar 21, 2018

Mar 14, 2018

  • "Transmission and resistance evolution of vancomycin resistant Enterococcus faecium in a hospital" - Dr. Robert J. Wood,Assistant Professor, UM Medical School, Division of Infectious Diseases

Mar 07, 2018

  • “Machine Learning for Understanding the Dynamics of Cell Populations”- Jie Liu, Ph.D., University of Washington

Feb. 21, 2018

  • "The power of one: Novel perspectives from single cell sequencing of the testis"(PASSWORD PROTECTED) - Dr.Sue Hammoud, University of Michigan

Feb 14, 2018

Feb 07, 2018

Jan 31, 2018

Jan 24, 2018

Jan 10, 2018

2017 Seminar Video Archive

Dec 06, 2017

Nov 15, 2017

Oct 04, 2017

  • "Listening to and re-writing the molecular songs of muscle regeneration using integrative genomics and single-molecule sensors" - by Dr. Carlos Aguilar

Sep 27, 2017

Sep 20, 2017

Sep 06, 2017

Apr 12, 2017

  • "Beta cell endoplasmic reticulum homeostasis and COPII dependent export in health and diabetes" - by Dr.Xuequn Chen, Wayne State University

Apr 05, 2017

Mar 29, 2017

  • "Genetic and epigenetic determinants of gene regulation in normal cells and cancer" - byDr. Vishy Iyer (Recording availableby request.)

Mar 15, 2017

Mar 08, 2017

Feb 08, 2017

Jan 25, 2017

Jan 18, 2017

Jan 11, 2017

2016 Seminar Video Archive

Dec 13, 2016

Nov 02, 2016

Oct 26, 2016

  • "Integrative Analysis of Data from The Cancer Genome Atlas" - by Dr. Ilya Shmulevich, Professor, Institute for Systems Biology

Oct 19, 2016

  • "Differential Expression Analysis for RNAseq using Poisson Mixed Models" - by Dr. Dr. Xiang Zhou

Oct 12, 2016

  • "Human Genetics Defines New Causes and Possible Treatments for Human Obesity and Nonalcoholic Fatty Liver Disease" - by Dr. Elizabeth Speliotes

Sep 28, 2016

  • Panel of Biological Networks - by Dr. Megan Duffy and Dr. Indika Rajapakse

Sep 21, 2016

  • "Mapping Brain Networks with Functional Connectomics: Can We Solve the Biomarker Problem in Psychiatry?" - Dr. Chandra Sekhar Sripada

Sep 15, 2016

  • "The Cancer Genome Atlas: A Resource for Molecular Biology Studies" - Dr. Chad Creighton,Baylor College of Medicine

Sep 07, 2016

  • "Ontology – Having relationship is a complicated thing" -Dr. Sirarat Sarntivijai,European Bioinformatics Institute (EMBL-EBI)

Jul 18, 2016

  • "Casting a genome-wide (regulatory) net: From distributed SNPs towards common mechanisms" -Dr. Thomas Werner, University of Michigan

Jun 09, 2016

  • "Epigenomics approaches provide novel biological and clinical insights for myeloid malignancies"-Dr. Tingtin Qin, University of Michigan

May 04, 2016

  • "Translating genetics to therapeutics: Uncovering and manipulating GWAS variant circuitry" -Dr. Manolis Kellis, Broad Institute of MIT and Harvard

Apr 20, 2016

  • "Translating genetics to therapeutics: Uncovering and manipulating GWAS variant circuitry" -Dr. Xiaoxia “Nina” Lin, University of Michigan

Apr 13, 2016

  • "Mechanical control and modeling of human pluripotent stem cells"-Dr. Jianping Fu,University of Michigan

Apr 06, 2016

  • “Genotypic Variability and the Quantitative Proteotype” -Dr. Ruedi Aebersold, ETH Zurich Institute for Molecular Systems Biology

Mar 30, 2016

  • "Lifetime exposome modeling" -Dr. Olivier Jolliet, University of Michigan

Mar 16, 2016

  • "Sex, drugs and funky rhythms: Insights from in silico models" -Dr. Colleen E. Clancy, University of California, Davis,

Mar 09, 2016

  • “Pharmacometabolomics: Metabolic Phenotyping of Drug Response” -Kathleen A. Stringer, PharmD, University of Michigan

Mar 02, 2016

  • “Nuclear Mechanics of Genome Reprogramming” -Dr. G.V.Shivashankar, Mechanobiology Institute, National University of Singapore, Singapore & FIRC Institute of Molecular Oncology (IFOM)

Mar 01, 2016

  • "Genomic Profiling of Adrenal and Brain Cancers" -Dr. Siyuan Zheng

Feb 25, 2016

  • "The shape of things to come: Insights into how 3D chromatin structure regulates gene expression and human development" -Dr. Douglas Phanstiel, Stanford University

Feb 17, 2016

  • “Genomically-Guided Personalized Medicine Clinical Trials” -Dr. Nicholas J. Schork, J. Craig Venter Institute

Feb 10, 2016

  • “Intelligent Transportation Using Big Data” -Dr. Jieping Ye, University of Michigan

Feb 03, 2016

  • "Dynamic Transcription Factor Activity Networks" -Dr. Lonnie Shea

Jan 27, 2016

  • "Emerging Questions in Quantitative Biology" - Panel Discussion

Jan 25, 2016

  • "4DN: Dynamics of the 3D Nucleome" -Dr. Indika Rajapakse

Jan 20, 2016

  • “Molecular- to population-level models of the gut immune-microbial ecosystem” -Dr. Emily R. Miraldi, Simons Center for Data Analysis, NYU School of Medicine

Jan 14, 2016

  • "Differential Expression of Splice Variants in Key Steps of Cancer Pathways" -Dr. Gilbert S. Omenn, University of MIchigan

Jan 13, 2016

  • “Cracking the regulatory genome: Which genetic variants affect gene regulation?” -Dr. Roger Pique-Regi, Wayne State University

Jan 11, 2016

  • Dr. Kathleen Stringer

2015 Seminar Video Archive

Dec 2, 2015

  • "Medical Internship as a Model to Identify Biological Predictors of Depression under Stress" -Dr. Srijan Sen

Nov 18, 2015

  • "Psychiatric Pharmacogenomics: Clinical Translation and Novel Variant Discovery" -Dr. Gerry Higgins

Nov 04, 2015

  • “Commensal Bacteria and Interferon-lambda Regulate Norovirus Persistence” -Dr. Megan T. Baldridge, Washington University in St. Louis

Oct 28, 2015

  • “Tools for studying RNA virus diversity” -Dr. Adam S. Lauring

Oct 21, 2015

  • “Large-scale structure in networks” -Dr. Mark E. Newman

Oct 07, 2015

  • Gilbert S. Omenn Lectureship: “Simulating the Motion of Proteins and Drug Molecules: Implications for Science and Medicine” -Dr. David E. Shaw, D.E. Shaw Research

Sep 30, 2015

  • "Towards Systems-Level Understanding of Immune Cell Communication and Inflammatory Tissue Environments: Applications in HIV/AIDS” -Dr. Kelly Arnold,

Sep 23, 2015

  • "Metabolomics: in vivo and in vitro" -Dr. Charles Burant

Sep 16, 2015

  • "Bioinformatics Colloquium Emerging Topics: Avoiding Pitfalls in Data Analysis" -Panel: Dr. Jun Li; Dr. Daniel Almirall; and Dr. James Joyce

Sep 09, 2015

  • “Computational Advances and Challenges in Proteomics” -Dr. Alexey Nesvizhskii,

Jun 17, 2015

  • “Genome-wide observations: Mutagenesis and instability of structural variations” -Dr. Arthur Zhou, Fudan University

Jun 03, 2015

  • "New Algorithms for Genome Comparisons" -Dr. Jian Ma, University of Illinois

May 06, 2015

  • "Emerging Questions in Quantitative Biology" -Dr. Gil Omenn, Dr. Daniel Kruger, & Dr. Robert Woods

Apr 29, 2015

  • "Developmental Control of Replication Timing and Chromosome Architecture" -Dr. David M. Gilbert, Florida State University

Apr 23, 2015

  • "What comes after Big Data: The role of dynamic knowledge representation in addressing the Translational Dilemma in the supercomputing age” -Dr. Gary An, University of Chicago

Apr 22

  • “Insights into the mechanisms of gene transcription from multi and single cell experiments” -Dr. Carson C. Chow, National Institutes of Health

Apr 15, 2015

  • “The epigenomic landscape at base-pair resolution” -Dr. Steven Henikoff, Fred Hutchinson Cancer Research Center

Apr 08, 2015

  • "Investigating the effects of macromolecular crowding on reaction kinetics, protein aggregation and cell physiology" -Dr. Santiago Schnell

Apr 01, 2015

  • “Disentangling the impacts of mutation and selection on regulatory variation” -Dr. Patricia Wittkopp

Mar 27, 2015

  • "Data Engineering on Spark" -Dr. Shuo Xiang, Pinterest

Mar 25, 2015

  • “Carrier Screening and All vs All Approximate K-mer Comparison” -Dr. Tobias P. Mann, Senior Director of Bioinformatics Progenity

Mar 18, 2015

  • “Integrating transcription, replication and de novo CNV data: Mechanisms of extreme genomic instability at large transcribed genes” -Dr. Tom Wilson

Mar 17, 2015

  • "Research Opportunities at Jassen" -Dr. Nicholas C. Dracopoli and Dr. Michael E. Schaffer, Janssen Research and Development

Mar 11, 2015

  • “Understanding the Cause and Consequence of Genomic Variation in Neurodevelopmental and Psychiatric Disorders” -Dr. Michael Talkowski,Center for Human Genetic Research, Massachusetts General Hospital, Harvard Medical School

Mar 10, 2015

  • “From Systems Genetics to Predictive Genomics: Harnessing genetic diversity to inform public health and transform disease research” -Dr. Steven Munger, Post-doctoral fellow The Jackson Laboratory Center for Genome Dynamics

Mar 09, 2015

  • “From Systems Genetics to Predictive Genomics: Harnessing genetic diversity to inform public health and transform disease research” -Dr. John Thomas Finnell, Indiana University, School of Medicine

Mar 04, 2015

  • “The Consensus Molecular Subtypes of Colorectal Cancer” -Dr. Justin Guinney, Sage Bionetworks

Feb 25, 2015

  • “Methods for the Identification of Unknown Features in Global Metabolomics Profiling Studies” -Dr. George Michailidis

Feb 18, 2015

  • “A Global Assessment of Sleep Schedules using Smartphone Data” -Dr. Daniel Forger

Feb 05, 2015

  • "Gene Discovery to Understand the Biology of Cardiovascular Disease" -Dr. Cristen J. Willer

Jan 28, 2015

  • “Beyond the Mendelian-Cartesian Paradigm, Human Genetics in the 21st Century” -Dr. Charles Sing,

Jan 21, 2015

  • "Emerging Properties in Biology" -Panelists - Dr. Mashour, Dr. Sterner, Dr. Simon,

Jan 07, 2015

  • “Large Scale Correlation Mining for Bio-molecular Network Discovery.” - Dr. Al Hero

2014 Seminar Video Archive

Dec 10, 2014

  • “Decoding the multi-drug response in bacterial populations” - Dr. Kevin Wood

Dec 03, 2014

  • “Genomic insights into the evolution and epidemiology of hospital-associated pathogens” - Dr. Evan Snitkin

Nov 19, 2014

  • “From protein structure to function and back again” - Dr. Sayan Mukherjee

Nov 07, 2014

  • “Dynamics of the genome” - Dr. Stephen Smale, Berkeley University

Oct 29, 2014

  • “Understanding gene regulation from the atom up” - Dr. Peter Freddolino

Oct 22, 2014

  • “Asymmetric stem cell division in tissue homeostasis” - Dr. Yukiko Yamashita

Oct 15, 2014

  • "A circadian gene expression atlas in mammals: implications for biology and medicine" - Dr. John Hogenesch, University of Pennsylvania

Oct 01, 2014

  • “The 4-D Genome In Vivo: First Steps toward a CRISPR Toolkit” - Dr. Thoru Pederson, University of Massachusetts Medical School

Sep 29, 2014

  • 2nd Annual Gilbert S. Omenn Lectureship - Dr. Isaac S. Kohane, Harvard Medical School

Sep 24, 2014

  • “Engineering protein interactions to reveal emergent cellular function” - Dr. Sivaraj Sivaramakrishnan

Sep 17, 2014

  • “4DN: Dynamics of the 3D Nucleome” - Dr. Indika Rajapakse

Sep 10, 2014

  • "Challenges and opportunities in applying next-generation sequencing to understanding the genetics of complex diseases" - Dr. Richard McCombie, Cold Spring Harbor

Sep 03, 2014

  • “The 4-D of Transcription Regulation” - Dr. Mats Ljungman

Aug 19, 2014

  • "Maximizing the Utility of TCGA Genomic Data: Tools, Analysis and Discovery" - Dr. Han Liang, The University of Texas MD Anderson Cancer

May 07, 2014

  • "Inferring Mechanisms from Protein and RNA Structures" - Robert L Jernigan, Iowa State University

Apr 22, 2014

  • "Techno-Innovations in Migraine and Pain Medicine" - Dr. Alexandre DaSilva, Biologic and Materials Sciences, University of Michigan Dental School

Apr 16, 2014

  • "Structural and functional analysis of heterotrimeric G protein signaling" - Dr. John Tesmer

Apr 09, 2014

  • “Integrating Structural and Systems Biology: Structure-based Prediction of Protein-Protein Interactions on a Genome-wide Scale” - Dr. Barry Honig, Columbia University

Apr 02, 2014

  • "New insights into neurodegenerative proteinopathies" - Dr. Henry Paulson

Mar 26, 2014

  • "Large-Scale Structured Sparse Learning for Biomedical Data" - Dr. Jieping Ye

Mar 24, 2014

  • "Integrative approaches for decoding the function of long non-coding RNAs in human cancer" - Dr. Yiwen Chen, Harvard University

Mar 19, 2014

  • "Detecting and Correcting Spurious Transcriptome Inference due to RNAseq Reads Misalignment" - Dr. Wei Wang, University of California, Los Angeles

Mar 05, 2014

  • "Self-Assembly of Nanoparticles: Biological Connection and Applications" - Dr. Nick Kotov

Feb 26, 2014

  • "Genomic Networks, Epistasis and Cancer" - Dr. Kevin White, University of Chicago

Feb 19, 2014

  • “Novel Approaches in Quantitative and Structural Proteomics for Clinical Research and Diagnostics” - Dr. Christoph H Borchers, University of Victoria

Feb 03, 2014

  • "Single cell transcriptomics: Exploring cellular heterogeneity in immune response" - Dr. Rahul Satija, Broad Institute

Jan 29, 2014

  • "The Gold mine in Eukaryotic Genomes – Identification of Small RNA Pathway and Human Disease Loci Genes from Eukaryotic Genomes" - Dr. Yuval Tabach, Harvard University

Jan 27, 2014

  • "Evolutionary Biology in a Big and Open Data World" - Dr. Stephen Smith

Jan 22, 2014

  • "Gene Regulatory Network Estimation" - Dr. Matthew McCall, University of Rochester Medical Center

Jan 15, 2014

  • "Enhancer biology in disease: stretch enhancers in type 2 diabetes" - Dr. Stephen Parker, NIH

Jan 08, 2014

  • "In Silico Techniques for Delivering Quality Healthcare" - Dr. Qian Zhu, Mayo Clinic

2013 Seminar Video Archive

Nov 25, 2013

  • "Controlling protein function via hidden allosteric sites" - by Dr. Gregory Bowman, University of California, Berkeley

Nov 21, 2013

  • "Sex-biased evolution and disease" - by Dr. Melissa Wilson Sayres, Center for Theoretical Evolutionary Genomics, UC Berkeley

Nov 20, 2013

  • "Inhibitor Discovery for a Respiratory Enzyme and G-protein Coupled Receptor Using a Trio of Structure-based Screening Techniques" - by Dr. Leslie Kuhn, Michigan State University

Nov 13, 2013

  • "A novel strategy for treatment and early diagnosis of Alzheimer disease: molecular chaperones acting as a physiological inhibitor of Tau fibrillization" - by Dr. Yi Liang, University of Michigan

Nov 06, 2013

  • "Genome and Transcriptome Dynamics in Cancer Cells" - by Dr. Thomas Ried, National Institutes of Health

Oct 30, 2013

  • "Strategy and Progress of the HUPO Human Proteome Project, with Highlights from the Chromosome 17 Team" - by Dr. Gilbert S. Omenn, University of Michigan

Oct 28, 2013

  • "A Systems Approach to Disease: Dynamics and Diagnostics" - by Dr. Leroy Hood, Institute for Systems Biology

Oct 23, 2013

  • “Climbing the scales ladder from protein chemistry to population biology” - by Dr. Eugene Shakhnovich, Harvard University

Oct 16, 2013

  • “Computational approaches to systematic understanding of transcriptome landscape” - by Dr. Dong Xiao Zhu, Wayne State University

Oct 02, 2013

  • "Protein Association in Dilute and Crowded Solutions" - by Dr. Huan-Xiang Zhou, Florida State University

Sep 25, 2013

  • "Modeling the assembly and disassembly of multi-domain structures of alpha-actinin-4 explains how external cues regulate actin binding" - by Dr. Carlos J. Camacho, University of Pittsburgh

Sep 18, 2013

  • "Automated Prediction of Molecular Assemblies" - by Dr. Chandra Bajaj, University of Texas, Austin

Sep 11, 2013

  • “The tranSMART Platform and the tranSMART Foundation: Global Cyberinfrastructure for Integrative Informatics Analysis” - by Dr. Brian Athey, University of Michigan

Aug 21, 2013

  • "Dynamic Perturbed Networks in a Mouse Model of Huntington's Disease" - by Dr. Nathan Gooman, Institute for Systems Biology

Jun 05, 2013

  • “Flourescence Microscopy at Molecular Optical Resolution” - by Dr. Christoph Cremer, University of Heidelberg, Kirchhoff-Institute for Physics

May 08, 2013

  • “An integrative systems approach to understanding cell type-specific gene regulatory networks, and its application to macrophages in atherosclerosis” - by Dr. Stephen Ramsey, Institute for Systems Biology

May 07, 2013

  • “Approach to protein structure-based function annotation and drug discovery” - by Dr. Jianyi Yang

May 01, 2013

  • “Development rooted in emergent properties of regulatory networks” - by Dr. Philip Benfey, Duke University

Apr 24, 2013

  • "Circadian clock-gated cell division cycles in Neurospora crassa Development rooted in emergent properties of regulatory networks"
    - by Dr. Chris Hong, University of Cincinnati

Apr 16, 2013

  • "Mathematics of Protein Folding" - by Dr. Stephen Smale, City of Hong Kong University

Apr 10, 2013

  • “A Systems Biology Approach to Uncovering Mechanisms Governing Host-Mycobacterial Interactions during TB Infection” - by Dr. Denise Kirschner, University of Michigan

Apr 03, 2013

  • “How Time Flies in Drosophila Circadian Clocks” - by Dr. Ravi Allada, Northwestern University

Mar 27, 2013

  • "Dynamics of the Microbiome" - by Dr. Pat Schloss, University of Michigan

Mar 25, 2013

  • "Understanding cellular heterogeneity using single-cell data" - by Dr. Peng Qiu, The University of Texas MD; Anderson Cancer Center, Houston, TX

Mar 20, 2013

  • “Strategies for improving multiscale, explanatory mechanistic insight in the face of pervasive uncertainty and persistent, intractable experimental variability” - by Dr. C. Anthony Hunt, University of California, San Francisco

Mar 13, 2013

  • “Statistical shape analysis of cerebellar MRI” - by Dr. Sarah Ying, John Hopkins University

Mar 04, 2013

  • “Biological Networks in Three Dimensions” - by Dr. Yu Xia

Feb 26, 2013

  • - by Dr. Kevin White, University of Chicago

Feb 13, 2013

  • “Challenges in designing inhibitors of protein-protein interactions” - by Dr. Tomasz Cierpicki, University of Michigan

Jan 30, 2013

  • “A Systems Biology Approach to Understanding the Immune Response in Tuberculosis” - by Dr. Simeone Marino, University of Michigan

Jan 16, 2013

  • “Functional connectomics and the search for biomarkers in psychiatric imaging” - by Dr. Chandra Sekhar Sripada, University of Michigan

Jan 09, 2013

  • “Categorical Spectral Analysis of Periodicity in Human and Viral Genomes” - by Dr. Jun S. Song, University of California, San Francisco