Indika Rajapakse, PhD
Professor of Computational Medicine and Bioinformatics
Professor of Mathematics
College of Literature, Science, and the Arts
[email protected]

Available to mentor
Indika Rajapakse, PhD
Professor
  • Qualifications
  • Center Memberships
  • Research Overview
  • Links
  • Recent Publications
    • Qualifications
    • Postdoctoral Fellow
      Fred Hutchinson Cancer Research Center, Genome Cell Biology, 2012
    • Postdoctoral Fellow
      Los Alamos National Laboratory, Applied Mathematics, 2006
    Center Memberships
    • Center Member
      Rogel Cancer Center
    • Center Member
      Biosciences Initiative
    Research Overview

    The work in our lab is focused on the dynamics of genome organization in human cells, with emphasis on gaining a deeper understanding of how the cell cycle guides cell fate determination. The long-term goal is to develop strategies for direct reprogramming of normal and abnormal cells. Another area of research is Data-guided Learning and Control of Higher Order Structures.

    Links
    • Rajapakse Lab
    Recent Publications See All Publications
    • Preprint
      A lipid-associated macrophage lineage rewires the spatial landscape of adipose tissue in early obesity
      Stansbury C, Dotson G, Pugh H, Rehemtulla A, Rajapakse I, Muir L. 2022 bioRxiv, DOI:10.1101/2022.02.26.482134
    • Preprint
      A lipid-associated macrophage lineage rewires the spatial landscape of adipose tissue in early obesity
      Stansbury C, Dotson G, Pugh H, Rehemtulla A, Rajapakse I, Muir L. 2022 bioRxiv, DOI:10.1101/2022.02.26.482134
    • Preprint
      Rearrangement of T Cell Genome Architecture Regulates GVHD
      Sun Y, Dotson GA, Muir LA, Ronquist S, Oravecz-Wilson K, Peltier D, Seike K, Li L, Meixner W, Rajapakse I, Reddy P. 2022 Jan 1; SSRN Electronic Journal, DOI:10.2139/ssrn.4022705
    • Preprint
      Rearrangement of T Cell Genome Architecture Regulates GVHD
      Sun Y, Dotson GA, Muir LA, Ronquist S, Oravecz-Wilson K, Peltier D, Seike K, Li L, Meixner W, Rajapakse I, Reddy P. 2022 Jan 1; SSRN Electronic Journal, DOI:10.2139/ssrn.4022705
    • Journal Article
      Functional organization of the maternal and paternal human 4D Nucleome.
      Lindsly S, Jia W, Chen H, Liu S, Ronquist S, Chen C, Wen X, Stansbury C, Dotson GA, Ryan C, Rehemtulla A, Omenn GS, Wicha M, Li SC, Muir L, Rajapakse I. iScience, 2021 Dec 17; 24 (12): 103452 DOI:10.1016/j.isci.2021.103452
      PMID: 34877507
    • Journal Article
      Functional organization of the maternal and paternal human 4D Nucleome.
      Lindsly S, Jia W, Chen H, Liu S, Ronquist S, Chen C, Wen X, Stansbury C, Dotson GA, Ryan C, Rehemtulla A, Omenn GS, Wicha M, Li SC, Muir L, Rajapakse I. iScience, 2021 Dec 17; 24 (12): 103452 DOI:10.1016/j.isci.2021.103452
      PMID: 34877507
    • Journal Article
      Conversation with dr. Steve Smale and dr. lee Hartwell
      Rajapakse I. Notices of the American Mathematical Society, 2021 Oct 1; 68 (9): 1578 - 1582. DOI:10.1090/noti2356
    • Journal Article
      Conversation with dr. Steve Smale and dr. lee Hartwell
      Rajapakse I. Notices of the American Mathematical Society, 2021 Oct 1; 68 (9): 1578 - 1582. DOI:10.1090/noti2356
    Featured News & Stories AI-generated fantasist illustration with two identical cells in a blueprint style
    Department News
    A new grant for the Rajapakse lab
    The Rajapakse lab receives a new grant.
    Department News
    2023 Faculty Promotions and Accolades
    2023 Faculty Promotions and Accolades at the U-M Department of Computational Medicine and Bioinformatics (DCMB).
    Department News
    BAB in the Lab
    BAB is a tall, quiet, and infatigable robot. BAB lives at the University of Michigan North Campus Research Complex, in Dr. Indika Rajapakse’s lab.