Areas of Interest
Dr. Guest obtained his bachelor of science degree in Microbiology at the University of Michigan where he studied gene regulation in the laboratory of Dr. Jessica Schwartz. He completed his Ph.D. at the University of Chicago where his thesis work uncovered the molecular mechanisms responsible for the effectiveness of the live, attenuated strains of the polio virus vaccine. As a post-doc, Dr. Guest entered the world of genomics working to develop approaches for performing genome-wide functional genetic screens in cultured cell lines. After joining the faculty in the Hollings Cancer Center at the Medical University of South Carolina, Dr. Guest led a research team that was focused on applying genome-wide functional genetic screens and computational approaches to the discovery of novel therapeutic strategies for breast cancer. In 2017, Dr. Guest joined the Department of Computational Medicine and Bioinformatics at the University of Michigan. As a member of the DCM&B he designs and teaches bioinformatics courses, guides curriculum development, and serves as an advisor for the Master’s program. Dr. Guest has a passion for teaching, research, and helping students on their journey through graduate school.