Lecturer IV in Computational Medicine and Bioinformatics
[email protected]
Available to mentor
Stephen T Guest, PhD
Lecturer
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Turner-Ivey B, Longo JF, Jenkins DP, Guest ST, Carroll SL. J Vis Exp, 2023 Aug 25; (198):Journal ArticleGenetic Profiling and Genome-Scale Dropout Screening to Identify Therapeutic Targets in Mouse Models of Malignant Peripheral Nerve Sheath Tumor.
DOI:10.3791/65430 PMID: 37677047 -
Ethier SP, Guest ST, Garrett-Mayer E, Armeson K, Wilson RC, Duchinski K, Couch D, Gray JW, Kappler C. NPJ Breast Cancer, 2020 6: 30Journal ArticleDevelopment and implementation of the SUM breast cancer cell line functional genomics knowledge base.
DOI:10.1038/s41523-020-0173-z PMID: 32715085 -
Rutkovsky AC, Yeh ES, Guest ST, Findlay VJ, Muise-Helmericks RC, Armeson K, Ethier SP. BMC Cancer, 2019 May 23; 19 (1): 491Journal ArticleEukaryotic initiation factor 4E-binding protein as an oncogene in breast cancer.
DOI:10.1186/s12885-019-5667-4 PMID: 31122207 -
Homer-Bouthiette C, Zhao Y, Shunkwiler LB, Van Peel B, Garrett-Mayer E, Baird RC, Rissman AI, Guest ST, Ethier SP, John MC, Powers PA, Haag JD, Gould MN, Smits BMG. BMC Cancer, 2018 Dec 10; 18 (1): 1233Journal ArticleDeletion of the murine ortholog of the 8q24 gene desert has anti-cancer effects in transgenic mammary cancer models.
DOI:10.1186/s12885-018-5109-8 PMID: 30526553 -
Irish JC, Mills JN, Turner-Ivey B, Wilson RC, Guest ST, Rutkovsky A, Dombkowski A, Kappler CS, Hardiman G, Ethier SP. Mol Oncol, 2016 Jun; 10 (6): 850 - 865.Journal ArticleAmplification of WHSC1L1 regulates expression and estrogen-independent activation of ERα in SUM-44 breast cancer cells and is associated with ERα over-expression in breast cancer.
DOI:10.1016/j.molonc.2016.02.003 PMID: 27005559 -
Guest ST, Kratche ZR, Irish JC, Wilson RC, Haddad R, Gray JW, Garrett-Mayer E, Ethier SP. Oncotarget, 2016 Jun 14; 7 (24): 36138 - 36153.Journal ArticleFunctional oncogene signatures guide rationally designed combination therapies to synergistically induce breast cancer cell death.
DOI:10.18632/oncotarget.9147 PMID: 27153554 -
Guest ST, Kratche ZR, Bollig-Fischer A, Haddad R, Ethier SP. Exp Cell Res, 2015 Mar 15; 332 (2): 223 - 235.Journal ArticleTwo members of the TRiC chaperonin complex, CCT2 and TCP1 are essential for survival of breast cancer cells and are linked to driving oncogenes.
DOI:10.1016/j.yexcr.2015.02.005 PMID: 25704758 -
Kappler CS, Guest ST, Irish JC, Garrett-Mayer E, Kratche Z, Wilson RC, Ethier SP. Mol Oncol, 2015 Feb; 9 (2): 527 - 543.Journal ArticleOncogenic signaling in amphiregulin and EGFR-expressing PTEN-null human breast cancer.
DOI:10.1016/j.molonc.2014.10.006 PMID: 25454348
Department News
Four DCMB alumni shared their experience building their career.
