Clinical Trials Info:

Rosacea Clinical Studies

Exploring gastrointestinal bacterial colonization in rosacea as a biomarker for systemic abnormalities in innate immunity

Enrollment status: Open

Rosacea is a common chronic inflammatory skin disease that affects 2-3% of the population in the United States. The exact cause of rosacea remains unclear, but many contributing factors have been established. For this study, we will seek to learn if an abnormal amount of bacterial colonization of the gastrointestinal (GI) tract leads to an abnormality in the body's natural and automatic defense system and contributes to the development of rosacea. The relationship between gastrointestinal (GI) bacteria and rosacea has been proposed in the past, but this study will serve to validate that claim. We will compare the gastrointestinal bacterial colonization in subjects with rosacea and those without rosacea using a standard breath testing and stool analysis methods. Blood testing will be performed to profile immune responses correlating with colonization.

Study coordinator: Mio Nakamura, MD, (734) 936-7519 or
Please reference Derm #: 682

Molecular Immunology of Papulopustular Rosacea

Enrollment status: Open

This observational study will compare the inflammatory process of rosacea to acne in skin samples. You must have active papulopustular rosacea or inflammatory acne to be considered for the study. Participants can complete the study in one visit:
- Research staff will perform a clinical assessment of your rosacea/acne
- Researcher will review your medical history and medication you are taking
- You will have photographs taken limited to the site of the biopsy.
- Skin biopsies will be obtained by a method called punch biopsy of the skin. The maximum punch size will be 3 mm. The skin will be numbed with a painkiller Lidocaine before the biopsy procedure.

Study coordinator: Lina Nahlawi, (734) 936-4075 or
Please reference Derm #: 737