The Center for Cutaneous Bioinformatics (CCB) aims to enhance the analysis and translation of experiments that study the genetics and genomics of different skin conditions. CCB researchers are developing novel systems biology approaches and analysis pipeline to decipher the pathology and mechanisms of cutaneous diseases. This research combines in silico discoveries and bench experiments to advance our understanding of genomics in autoimmune skin disorders. Modeling the risk of developing disease subtype and providing functional characterization of disease-associated long non-coding RNAs (lncRNAs) are two of the major projects for CCB.
- Integrative Biology Approach to Identify and Characterize Roles of long non-coding RNAs Associated with Psoriasis Pathology (NIH/NIAMS 1K01AR072129; PI: TSOI)
- Immunogenomics and Systems Biology Core (ISCB (NIH/NIAMS 1TUC2ActAR081033; Multi-PI: Gudjonsson, Tsoi, Welch, Zhou)
- UM-SBDRC Functional Analytics Core (NIH/NIAMS 5TP30ActAR075043; PI:Gudjonsson)