Our Aging Skin/Photobiology of Skin research team seeks to further our fundamental knowledge of the molecular mechanisms that give rise to age-related degeneration of the dermal extracellular matrix, with long-term aim of delaying these changes to improve the health of skin in the elderly.
Aging Skin and Photobiology of Skin
Center for Cutaneous Bioinformatics
The Center for Cutaneous Bioinformatics (CCB) is using systems biology approaches to advance our research discovery in skin biology and cutaneous disorders. Our researchers seek to implement efficient data-analysis frameworks to provide mechanistic understanding of cutaneous diseases by facilitating the interpretation and translation of high throughput experiments.
Autoimmunity/Immunogenetics in Skin
The Autoimmunity/Immnogenetics in Skin research team is investigating the genetic etiology and immune-pathogenesis of psoriasis and other autoimmune diseases that involve the skin.
Psoriasis Genomics and Pathophysiology
The U-M Psoriasis Genomics & Pathophysiology research program is a world leader in the use of molecular biology and genetic linkage and association techniques to elucidate how the immune system activates the epidermal wound healing mechanism in psoriasis, and joint destruction in psoriatic arthritis.
Skin Biology and Cancer
Our Skin Biology and Cancer research teams are investigating the genetics and signaling mechanisms underlying the initiation, development, and maintenance of skin tumors; treatment response and tumor dormancy; and the basic biology of skin and epithelial appendages.