Pilot and Exploratory Studies Core (PESC)

The goal of the Pilot and Exploratory Studies Core is to provide support for studies that will develop and test new research ideas of high relevance to the Center's overall theme:

“To improve understanding of how metabolic factors and inflammation interact with age-related diseases and comorbidities to determine key health outcomes related to mobility and functional status”

The PESC will thus fund pilot research studies over a wide range of disciplines, ranging from basic genetics and physiology through behavioral and health services research.

2018-2019 Pilot Grant Awardees:

    • Laura Zahodne - Inflammation, social stress, and racial disparities in cognitive aging

https://lsa.umich.edu/psych/people/faculty/lzahodne.html

    • Joshua Ehrlich - Vision Impairment and Mental Health Among Older Adults in Low and Middle Income Countries

https://medicine.umich.edu/dept/ophthalmology/joshua-r-ehrlich-md-mph

    • Scott Soleimanpour - Mitophagy as a regulator of glucose homeostasis in aging and obesity

http://cmb.medicine.umich.edu/scott-soleimanpour-phd

    • Andre Monteiro da Rocha - Epigenetic alterations associated in human cardiomyocytes with a Lamin A mutation causative of premature aging and proteasome activation as a potential therapeutic target

https://sites.google.com/umich.edu/cardio-regen-corelab/about-us

    • Geoffrey Hoffman - Exploring the Proportions of 30-Day Readmissions Associated with Fall-Related Injuries and Hospital-Acquired Infections

https://nursing.umich.edu/faculty-staff/faculty/geoffrey-j-hoffman

    • Shannon Moore - A novel discrimination learning paradigm to longitudinally assess age-related cognitive decline and treatment efficacy over the lifespan

https://sites.google.com/a/umich.edu/murphy-lab/people

    • Svetlana Stamatovic - Blood-brain barrier dysfunction after sepsis in aging mice: role for complement C5a and histories

https://www.pathology.med.umich.edu/faculty/sstamato

    • Maria Papaleontiou - Overtreatment with thyroid hormone and its effects on the cardiovascular system in older adults

https://www.uofmhealth.org/profile/3187/maria-papaleontiou-md

    • Navid Serajo-Bozogzad - Cortical Microstructural Changes in African-Americans with Alzheimer’s Disease

https://www.medicine.umich.edu/dept/neurology/navid-seraji-bozorgzad-md

 

 

 

Core Director:

Lona Mody, M.D., M.Sc.

Amanda Sanford Hickey Professor of Internal Medicine
Associate Division Chief, Geriatric & Palliative Care Medicine
Director, UM Pepper Center Pilot & Exploratory Studies Core
Associate Director, Clinical and Translational Research, Geriatrics Center

Core Co-Director:

Daniel R. Goldstein, M.D.

ELIZA MARIA MOSHER COLLEGIATE PROFESSOR IN INTERNAL MEDICINE
RESEARCH PROFESSOR, INSTITUTE OF GERONTOLOGY
DIRECTOR, MICHIGAN BIOLOGY OF CARDIOVASCULAR AGING (M-BoCA)
734-936-1193