Downloads - Disease Modeling Software for Clinical Research

Michigan Model for Diabetes: Version 2.0 – Sept 1, 2015

Download Michigan Model for Diabetes: Version 2.0 New features of the MMD 2.0 include:       
  1. Modeling disease progression as a function of the changes in multiple biomarkers and risk factors
  2. An updated coronary heart disease sub-model that incorporates the possibility of recurrence of myocardial infarction (MI), congestive heart failure, and cardiac procedures either before or after MI
  3. Modeling modern diabetes treatment regimens and management for dysglycemia, dyslipidemia, and hypertension
  4. Modeling the direct benefit of medication and compliance
  5. Updated transition probability tables for end stage renal disease
  6. Updated competing death table
  7. Updated cost and utility models


Michigan Model for Diabetes: Version 1.0 – May 11, 2009
Download Michigan Model for Diabetes: Version 1.0         


Indirect Estimation and Simulation Tool (IEST)
Download Version - 27-Feb-2012

Please note: the user manual for MMD 2.0 is included with the software. You can also download the manual separately here:

Remember to cite the Michigan Center for Diabetes Translational Research (MCDTR) in publications as follows:
“The project described was supported by Grant Number P30DK092926 (MCDTR) from the National Institute of Diabetes and Digestive and Kidney Diseases”