MDRC Chemistry Laboratory

The Michigan Diabetes Research Center's Chemistry Laboratory is a clinical core providing many assays related to diabetes, heart disease, and hypertension.

The MDRC Chemistry Laboratory is part of the University of Michigan’s MiCORES system. 

In order to use the MDRC Chemistry Laboratory’s services, you must be a registered user in the University of Michigan’s MiCORES system.  The instructions to register can be found below.

Once you are a registered user in the MiCORES system, it is necessary to complete the Consultation Request found on the MDRC Chemistry Laboratory’s MiCORES page for all new studies/projects.

After you submit this information, laboratory personnel will reach out to you to review your project and develop an aliquoting scheme for the assays you have requested. The MDRC Chemistry Laboratory's aliquoting scheme will group the assays/sample types in such a way to minimize the number of freeze-thaw cycles (FTC) for the samples and will also minimize the number of aliquots that need to be prepared at the time of sample collection.

Once this review/approval process is complete, you will receive a MDRC Chemistry Laboratory Project Number. This number will be used in conjunction with the Sample Submission Form found on the MDRC Chemistry Laboratory’s MiCORES page for all future sample submissions associated with this project.

The MDRC Chemistry Laboratory currently offers thirty-four (34) different individual assays. Species, sample type, minimum batch size, minimum sample volume, and per sample pricing is available on our Request Services tab in the Service List section of the MDRC Chemistry Laboratory’s MiCORES page. If your analyte is not on this list, please contact the laboratory using the Contact Us tab on the MDRC Chemistry Laboratory’s MiCORES page as we may be able to add it.

Individual assays include:

 

 

The MDRC Chemistry Laboratory offers multiplex services featuring Millipore Sigma’s MILLIPLEX® catalog of panels on a Luminex™ 200™ Instrument System. These panels offer a broad selection of analytes measured from a single, small volume sample. Panels are available for human, mouse, rat, and more. Sample types include serum, plasma and cell culture. A list of available panels can be found can be found on the MDRC Chemistry Laboratory MiCORES page.  Each panel is customizable within the group of analytes available on that particular panel. You can choose any combination (in most cases) and any number of analytes on each pre-defined panel. The panels are custom ordered from Millipore Sigma using the investigator’s recharge account and are shipped directly to the MDRC Chemistry Laboratory. In addition to the panel cost, each panel will be charged a labor/report writing fee ($250 per panel).

The MDRC Chemistry Laboratory offers ELISA services as well. We have a handful of ELISA’s that we offer regularly to our diabetes research community such as mouse leptin, adiponectin, c-peptide, and insulin, but we may also be able to run your specifically chosen ELISA panel. Once we determine we can run your specific ELISA panel, you can either provide the ELISA panel with the samples or we can order the panel for you. If we order the panel for you, the investigator’s recharge account will be used to purchase the panel and it will be shipped directly to the MDRC Chemistry Laboratory. In addition to the panel cost, each panel (supplied by you or purchased by us) will be charged a labor/report writing fee ($250 per panel). If you would like ask if we can run your specific ELISA panel or your specific analyte via ELISA, please use the Contact Us tab on the MDRC Chemistry Laboratory MiCORES page.

Key Personnel

David Manthei, MD, PhD

Laboratory Director

Jason Whalen, BS

Research Associate

For more information contact:

Jason Whalen
Medical Sciences Research Building 2 Sub-Basement Level C, Room C562
1150 W Medical Center Drive
Ann Arbor, MI 48109

Remember to cite the Michigan Diabetes Research Center (MDRC) in publications as follows:
“The project described was supported by Grant Number P30DK020572 (MDRC) from the National Institute of Diabetes and Digestive and Kidney Diseases”