UM Faculty Research Programs

Program for Clinical Research in Diabetes Care and Complications

Rodica Pop-Busui, MD, PhD headshot

Our mission is to advance the knowledge in the field of diabetes and its complications, while improving the clinical care and life of all patients with diabetes in the U.S. and worldwide.  

Rodica Pop-Busui, MD, PhD, Larry D. Soderquist Professor, who leads the research program, is a Professor in the Department of Internal Medicine in the Division of Metabolism, Endocrinology & Diabetes (MEND), Co-Director of the Michigan Peripheral Neuropathy Center at U-M, and Vice Chair, Clinical Research at the University of Michigan.

An endocrinologist, diabetologist, clinician, researcher, and scholar, Dr. Pop-Busui is the leading physician in the field of diabetic complications within the University of Michigan's MEND Division. Her clinical interests are diabetes, diabetes complications, and metabolic syndrome. 

Dr. Pop-Busui’s research interest has focused on translational and clinical trials to study the mechanisms of diabetic complications, including diabetic cardiovascular autonomic and peripheral neuropathy, and to understand their role in the development of the high cardiovascular risk complicating diabetes.

Program for Translational Research in Diabetes & Metabolic Diseases

Dr. Elif Oral, MD

We are at an exciting time for metabolic research. Significant mechanistic knowledge is gained in the laboratories using powerful, novel technologies. Most of the knowledge is obtained from laboratory animals and in artificial experimental settings that cannot accurately proximate human homeostasis. Thus, it is important to bring clinical expertise closer to the laboratory bench. It is also important to take concepts and mechanisms obtained at the bench closer to the patients' problems seen in clinic. We are committed to achieving this mission for disorders of human adiposity and related metabolic problems. We have a track record of being able to accomplish this in a rare human condition. We have learned valuable lessons from our unique experience in lipodystrophy syndromes and would like to see if these lessons can be applied to more common human conditions with related metabolic problems.

Elif A. Oral, MD, MS, who leads the research program, is a Professor in the Department of Internal Medicine in the Division of Metabolism, Endocrinology & Diabetes (MEND), Director of the Post Bariatric Clinic, and Director of the Obesity and Metabolic Disorders Program. She is an academic endocrinologist whose main research interests lie in examining the unifying consequences of having too much fat versus too little fat.

Center for Managing Chronic Disease

CMCD investigators work to build the capacity for effective chronic disease prevention and management. We emphasize improving systems of care for the most vulnerable members of communities around the world. Our projects take a systems approach to understanding and identifying the barriers faced by people with chronic illnesses, their social networks, clinical teams, and healthcare payers. We conduct innovative research and disseminate results that can help to change policy and practice. We accomplish these goals by bringing together teams of researchers, health professionals and community members, including experts in health behavior change, health technology, and implementation science.  Our clinician colleagues are experts in primary care, geriatrics, cardiovascular disease, diabetes, chronic pain, cancer, respiratory disease, and mental health.

With strong expertise in dissemination, program evaluation, and implementation science, we work to move important innovations from research to practice and adapt programs found effective in one context to new areas where they may also improve patients’ experience with care.  CMCD places a priority on ensuring that proven interventions reach the largest number of people, in particular, low-income families, racial/ethnic minority groups, non-English speakers, children, older adults, and women.  To do that, we emphasize rigorous science disseminated through traditional academic channels, as well as making available toolkits and training materials so that interventions found effect can be widely adopted.

Center for Eye Policy & Innovation

Our work at the University of Michigan Center for Eye Policy and Innovation spans many areas of health services research in ophthalmology. We work with collaborators from across the University of Michigan and beyond, using an interdisciplinary approach to address some of the most pressing issues facing patients and the delivery of eye care.