Dr. Simon Hogan has more than 20 years of experience in basic immunology research, concentrating in development of animal model systems to study allergic immunologic processes in health and disease. Dr. Hogan completed his PhD at the John Curtin School of Medical Research at the Australian National University, Canberra, Australia focused on the identification of the contribution of IL-5, eosinophils and CD4+ T cell–derived IL-4–dependent and –independent pathways to the induction of the asthma phenotype. After completion of his PhD, he was awarded the prestigious Australian NHMRC CJ Martin postdoctoral fellowship to study eosinophil-associated allergic gastrointestinal diseases under the tutelage of Professors Paul S. Foster University of Newcastle and Marc E. Rothenberg at Cincinnati Children’s. During this time, he pioneered the development of a new system to analyze gastrointestinal allergy by developing a critical experimental regimen in mice and identified a new and pivotal role for the chemokine CCL11 in eosinophil recruitment into the GI tract during intestinal inflammation. In 2004, he was appointed as an independent faculty within the Division of Allergy and Immunology at Cincinnati Children’s. His FARE- and NIH-funded research focused on delineating interactions at the immune- gastrointestinal epithelial interface under homeostasis and how alterations in these interactions can predispose to and modulate food-induced anaphylactic reactions. In 2018, he was appointed as the Askwith Research Professor of Food Allergy, in the Mary H. Weiser Food Allergy Center (MHWFAC), as well as Tenured Professor of the Department of Pathology, Research Professor University of Michigan Mary H. Weiser Food Allergy Center (MHWFAC), University of Michigan Medical School where he will continue to pursue his long-standing research interests in defining underlying immunological processes that predispose and exacerbate allergic reactions.
Photo Credit: Dustin Johnston