Genetics Training Program: Genetics Short Course

U-M Buhl Building
 

HUMGEN 630: Co-sponsored by the Genetics Training Program (GTP) and the Program in Cellular and Molecular Biology (CMB).

Fall and Winter terms, 1 credit each.

In this short course, GTP and CMB students invite outstanding internal and external scientists to give a seminar and to formally and informally interact with students.

The topic of the Winter 2024 Short Course, sponsored by Human Genetics, is “As the Ribonucleotide Turns: How Cells Exert Control, Ride Out Genomic Instability, and Gain Immunity." GTP-CMB Short Course Seminar Series _WINTER 2024 Schedule (image below).

Seminars are open to the University Community

GTP Short Course Recordings

CMB Short Course Recordings

 

Winter 2024: As the Ribonucleotide Turns: How Cells Exert Control, Ride Out Genomic Instability, and Gain Immunity

Tuesday, January 30, 2024

  • Lyle Simmons, Ph.D., Professor, Molecular, Cellular, and Developmental Biology, University of Michigan
  • Introductory Lecture: "Genome Instability Caused by Persistent RNA-DNA Hybrid Formation"
  • 3:00 p.m., Med Sci 2 - West Lecture Hall

Tuesday, February 20, 2024

  • Francesca Storici, Ph.D., Professor and Associate Chair for Graduate Education, School of Biological Sciences, Georgia Institute of Technology
  • "RNA's Transformative Impact: Shaping DNA Metabolism in the Genome"
  • 3:00 p.m., Med Sci 2 - West Lecture Hall

Tuesday, March 19, 2024

  • Hai Dang Nguyen, Ph.D., Assistant Professor, Department of Pharmacology, University of Minnesota
  • "Understanding and Targeting R-Loop Response Pathways in Cancers"
  • 3:00 p.m., Med Sci 2 - West Lecture Hall

Tuesday, April 2, 2024

  • Nicholas Ingolia, Ph.D., Associate Professor, Department of Molecular and Cell Biology, University of California, Berkeley
  • "Global Analysis of the Networks Controlling mRNA Translation and Decay"
  • 3:00 p.m., Med Sci 1 - 3330 Auditorium

Tuesday, April 9, 2024

  • Wendy V. Gilbert, Ph.D., Professor of Molecular Biophysics and Biochemistry, School of Medicine, Yale University
  • "Decoding the Untranslated to Engineer Next-Generation mRNA Medicines"
  • 3:00 p.m., Med Sci 2 - West Lecture Hall

 [accordion]

Fall 2023: Adapting to a Changing World: Sustainability in a Biological Context

Tuesday, September 19, 2023

  • Introductory Lecture, Marcy Balunas, Ph.D., Associate Professor of Microbiology and Immunology and Medicinal Chemistry at the University of Michigan
    "In a Changing World: Interrogating Specialized Metabolite Production in Host-Microbe Symbioses"
  • 3:00pm, In-Person Location: Med Sci I, Room M5330

Tuesday, September 26, 2023

  • Joanna Lee, Ph.D., Principal Scientist, Biochemical & Cellular Pharmacology at Genentech
    "Towards Sustainability in Drug Discovery: Development of a High-Throughput 3D Culture Model of Immune Excluded Tumor Microenvironments"
    3:00pm, In-Person Location: Med Sci I, Room M5330

Friday, October 6, 2023

  • Heather Olins, Ph.D., Assistant Professor of the Practice in the Biology Department at Boston College
    "Sustainability as a Key Component of Biology Education"
    3:00pm, In-Person Location: Med Sci I, Room M5330

Tuesday, October 17, 2023

  • Evan Appleton, Ph.D., Head of Stem Cell Biology / Reprogramming & Principal Scientist at Colossal Biosciences
    "Stem Cells for Conservation and De-Extinction"
    3:00pm, In-Person Location: Med Sci I, Room M5330

Tuesday, November 14, 2023 

  • Chris Hernandez, Ph.D., Professor of Bioengineering and Orthopaedic Surgery, Director, Health Innovations Via Engineering center at UCSF
    "Using Biology to Advance Engineering and Sustainability: Engineered Living Materials"
    3:00pm, In-Person Location: Med Sci I, Room M5330

 

[accordion]

Winter 2023: Against the Grain: Peculiar Twists in the Central Dogma

Tuesday, February 21, 2023

  • Hayley McLoughlin, Ph.D., Assistant Professor of Neurology & Assistant Professor of Human Genetics, University of Michigan
  • Introductory Lecture: "Antisense Oligonucleotides in Ataxia: Elucidating Disease Mechanisms and Therapeutic Opportunities"
  • 3:00 p.m., MSII - North Lecture Hall

Tuesday, March 14, 2023

  • Glenn Telling, Ph.D., Professor of Microbiology, Immunology, and Pathology & Director of the Prion Research Center, Colorado State University
  • "Transgenic Mouse Models to Investigate Mechanisms of Prion Replication and Strain Variation"
  • 3:00 p.m., MSII - North Lecture Hall

Tuesday, April 4, 2023

  • Francine Perler, Ph.D., Chief Executive Officer, Perls of Wisdom Biotech Consulting
  • "Serendipity Reveals Novel Processes: Intein Discovery, Function, and Applications"
  • 3:00 p.m., MSI - M5330

Tuesday, April 11, 2023

  • Laura Ranum, Ph.D., Director, Center for NeuroGenetics & Kitzman Family Professor of Molecular Genetics and Microbiology, University of Florida
  • "Repeat Associated Non-AUG Proteins in Neurologic Disease: Mechanistic Insights and Therapeutic Opportunities"
  • 3:00 p.m., MSII - North Lecture Hall

Tuesday, April 18, 2023

  • Stephen Goff, Ph.D., Higgins Professor Microbiology & Immunology and Department of Biochemistry & Molecular Biophysics, Columbia University
  • "Retroviral Replication: Breaking Most of the Rules"
  • 3:00 p.m., MSII - North Lecture Hall

 

[accordion]

Fall 2022: The Cellular Basis of Medical Revolutions

Tuesday, September 20, 2022

  • Introductory Lecture, Jonathan Sexton, Ph.D., Assistant Professor of Internal Medicine and Medicinal Chemistry
    University of Michigan
    "Morphologic Single-Cell Profiling, Organoids and Drug Repurposing"
  • 3:00pm, In-Person Location: Med Sci I, Room M5330 

Tuesday, September 27,  2022

Jesse Bloom, Ph.D., Professor, Basic Sciences Division and Herbold Computational Biology Program, Fred Hutch
"Interpreting the evolution of SARS-CoV-2"
3:00pm, Zoom Link: https://umich.zoom.us/j/95906439845

Tuesday, October 18, 2022

  • Jing-Ke Weng, Ph.D., Associate Professor of Biology, Core Member, Whitehead Institute, Mass. Institute of Tech. (MIT)
    "Harnessing plant metabolism for new catalysts, medicines, and materials"
    3:00pm, In-Person Location: MSI - M5330 

Tuesday, October 25, 2022 

  • Carmela Sidrauski, Ph.D., Stowers Institute for Medical Research, Howard Hughes Medical Institute
    "Mechanisms and pathophysiology of the Integrated Stress Response"
    3:00pm,  Zoom Link: https://umich.zoom.us/j/95177822795

Tuesday, November 8, 2022 

  • Tanya Parish, Ph.D., Professor of Pediatrics, Center for Global Infectious Disease Research, Seattle Children's Hospital
    "TBD"
    3:00pm, In-Person Location: MSI - M5330

 

[accordion]

 

Winter 2022: Mechanistic Insights into DNA Replication: The Beauty is in the Details

Wednesday, March 9, 2022

  • Introductory Lecture, Thomas E. Wilson, M.D., Ph.D., Department of Human Genetics
    "The Relationships Between Replication Stress, Repair and Rescue Mechanisms, and Mutation"                               

    3:00pm
    Location: North Lecture Hall - MSII or ZOOM https://umich.zoom.us/j/99503863764 passcode: 174146  

Tuesday, March 22, 2022

  • Thomas A. Kunkel, Ph.D., DNA Replication Fidelity Group, National Institute of Environmental Health Sciences
    "The Generation and Repair of Eukaryotic Nuclear DNA Replication Errors"

    3:00pm
    Location: ZOOM https://umich.zoom.us/j/99503863764 passcode: 174146  

Tuesday, March 29, 2022

  • Supriya Prasanth, Ph.D., Department of Cell and Developmental Biology, University of Illinois at Urbana-Champaign
    "Mechanisms of Genome Inheritance"

    3:00pm
    Location: West Lecture Hall - MSII or ZOOM https://umich.zoom.us/j/99503863764 passcode: 174146  

Tuesday, April 12, 2022 

  • Karlene Cimprich, Ph.D., Department of Biochemistry, Stanford University 
    "RNA Meets DNA: Dangerous Liaisons in the Genome"

    3:00pm
    Location: ZOOM https://umich.zoom.us/j/99503863764 passcode: 174146  

Tuesday, April 19 2022 

  • Mary Lilly, Ph.D., Division of Intramural Research, National Institute of Child Health and Human Development (NICHD)
    "The Essential Roles of Stress Response Pathways in Meiosis and Gametogenesis"

    3:00pm
    Location: West Lecture Hall - MSII or ZOOM https://umich.zoom.us/j/99503863764 passcode: 174146 

 

[accordion]

Fall 2021: Multi-omics in Unique Model Systems

Friday, September 17, 2021

  • Introductory Lecture, Carole Parent, Ph.D., Professor of Cancer Biology and Pharmacology, Life Sciences Institute, University of Michigan
    "Dictyostelium discoideum as a model system to study chemotaxis"
  • 3:00pm, In-Person Location: Med Sci I, Room M3330 

Friday, October 1, 2021

  • Sebastian Lourido, Ph.D., Department of Biology, Whitehead Institute, Massachusetts Institute of Technology (MIT)
    "Defining transitions in a parasitic life cycle"
    3:00pm, Passcode: 558741 Zoom Link: https://umich.zoom.us/j/92611749823 

Thursday, October 7, 2021

  • Gilles Laurent, Ph.D., Managing Director, Max Planck Institute for Brain Research
    "What can we learn about brain function by studying reptiles and cephalopods?"
    10:00am, Location: Passcode: 254888 Zoom Link: https://umich.zoom.us/j/99243045579 

Tuesday, October 26, 2021 

  • Alejandro Sánchez Alvarado, Ph.D., Stowers Institute for Medical Research, Howard Hughes Medical Institute
    "Understanding the sources of regenerative capacity in animals"
    3:00pm, Passcode: 473243 Zoom Link: https://umich.zoom.us/j/98060943083 

Monday, November 15, 2021 

  • Karen Maruska, Ph.D., Associate Professor of Biological Sciences, Louisiana State University
    "Visual-acoustic communication in a cichlid fish: genes, brains, and behavior."
    3:00pm, Passcode: 441875 Zoom Link: https://umich.zoom.us/j/95785393440

[accordion]

Winter 2021: The Intricacies of Transcription:
Coordinating Multiple Layers of Gene Regulation

Tuesday, February 2, 2021

  • Introductory Lecture, Kenneth Cadigan, Ph.D., Department of Molecular, Cellular, and Developmental Biology, University of Michigan LSA
    "Welcome to the Exciting World of Tandem and Interspersed DNA Repeats"
  • 3:00pm, ZOOM https://umich-health.zoom.us/j/94509280988 

Tuesday, February 16, 2021

  • Stephen Montgomery, Ph.D., Departments of Pathology and Genetics, Stanford University School of Medicine
    "Common and Rare Regulatory Variation in Genetic Disease"
    3:00pm, ZOOM https://umich-health.zoom.us/j/94509280988 

Tuesday, March 9, 2021

  • Karen Adelman, Ph.D., Departments of Biological Chemistry and Molecular Pharmacology, Harvard Medical School
    "Regulating Transcription and Coding and Non-Coding RNA Loci"
    3:00pm, Location: ZOOM https://umich-health.zoom.us/j/94509280988 

Tuesday, March 30, 2021 

  • Hernan Garcia, Ph.D., Departments of Genetics, Genomics, & Development and Physics, University of California, Berkeley
    "Dissecting Transcriptional Dynamics in Development One Burst at a Time"
    3:00pm, ZOOM https://umich-health.zoom.us/j/94509280988 

Tuesday, April 20, 2021 

 

Fall 2020: Seeing is Believing: Advancing Research with Scientific Microscopy

Wednesday, September 16, 2020

  • Introductory Lecture, Melanie Ohi, Ph.D., Associate Professor, Cell and Developmental Biology and Life Science Institute, University of Michigan
    “Seeing is Believing: The Power of Microscopy in the Biological Sciences”
    9:30am, Bluejeans Mtg.,  https://bluejeans.com/791630062

Wednesday, September 23, 2020

  • Margaret Gardel, Ph.D., Professor, Department of Physics, University of Chicago.  
    "Biophysical Control of Epithelial Architecture and Dynamics"
    3:15pm, Bluejeans Mtg., https://bluejeans.com/307078354

Tuesday, October 6, 2020

  • Edward Boyden, Ph.D. Professor, Department of Biological Engineering and Brain and Cognitive Sciences, MIT  
    “Tools for Analyzing and Controlling Biological Systems”
    3:00pm, Bluejeans Mtg., https://bluejeans.com/966346744

Tuesday, October 29, 2020

  • Julie Canman, Ph.D., Associate Professor of Pathology & Cell Biology, Columbia University  
    "Title of Talk - TBD"
    3:00pm, Bluejeans Mtg., https://bluejeans.com/467324338

Friday, November 13, 2020

  • Michael Angelo, Ph.D., Assistant Professor, Department of Pathology, Stanford University  
    "Linking Single Cell Function to Tissue Structure in Human Health and Disease with Multiplexed Ion Beam Imaging"
    3:00pm, Bluejeans Mtg. , https://bluejeans.com/254475047

 

Winter 2020: Centromeres, Telomeres, and Transposable Elements, Oh My!

Tuesday, February 18, 2020

  • Introductory Lecture, Jayakrishnan Nandakumar, Ph.D., Department of Molecular, Cellular, and Developmental Biology, University of Michigan LSA
    "Welcome to the Exciting World of Tandem and Interspersed DNA Repeats"
  • 3:00pm, Location WLH Med Sci II

Tuesday, February 25, 2020

  • Amanda Larracuente, Ph.D., Department of Biology, University of Rochester
    "Retroelements: Conserved Features of Drosophila Centromeres"
    3:00pm, Location WLH Med Sci II

Tuesday, March 17, 2020

  • Joseph Peters, Ph.D., Department of Microbiology, Cornell University
    "Variant CRISPR/Cas-enabled Transposition Systems in Natural and Programed Genome Modification"
    3:00pm, Location: REMOTE ATTENDANCE ONLY

Tuesday, March 31, 2020 - CANCELLED

  • Gary Karpen, Ph.D., Department of Molecular and Cell Biology, University of California, Berkeley
    "Interrogating Roles for Liquidity in Nuclear Organization and Function"
    3:00pm, Location WLH Med Sci II

Tuesday, April 14, 2020 - CANCELLED

  • Julie Cooper, Ph.D., Department of Biochemistry and Molecular Genetics, University of Colorado School of Medicine
    "Centromeres Impersonating Telomeres, and Other Forms of Deception at the Chromosome End"
    3:00pm, Location WLH Med Sci I

Fall 2019: Messing with the Messenger: The Role of RNA Modification in Biology

Tuesday, October 8, 2019

  • Introductory Lecture, Mats Ljungman, Ph.D., Professor of Radiation Oncology and Environmental Health Sciences, University of Michigan
    “The Epitranscriptome”
    3:00pm, M3330 Med Sci I

Thursday, October 24, 2019

  • Brenda Bass, Ph.D., Distinguished Professor of Biochemistry, University of Utah
    "C. elegans ADARs Antagonize Silencing of Cellular dsRNAs by the Antiviral RNAi Pathway"
    3:00pm, M3330 Med Sci I

Tuesday, October 29, 2019

  • Kate Meyer, Ph.D. Assistant Professor of Biochemistry, Duke University School of Medicine
    “Detecting m6A and Its Role in RNA Regulation”
    3:00pm, M3330, Med Sci I

Thursday, November 7, 2019

  • Joshua Rosenthal, Ph.D., Senior Scientist, The Eugene Bell Center, Marine Biological Laboratory, University of Chicago
    "Generation of Plasticity in the Cephalopod Brain by Editing mRNA"
    3:00pm, M3330 Med Sci I

 Thursday, November 14, 2019

  • Stacy Horner, Ph.D., Assistant Professor of Molecular Genetics & Microbiology, Duke University School of Medicine
    "m6A at the Virus-Host Interface"
    3:00pm, M3330 Med Sci I

 

Winter 2019: Contain Your Cells: Regulatory Design by Chromatin Organization and Phase Separation

Tuesday, January 22, 2019

  • Introductory Lecture, Kaushik Ragunathan, Ph.D., Department of Biological Chemistry, University of Michigan Medical School
    “Phase Separation as an Organizing Principle of Cellular Function”
    3:00pm, West Lecture Hall - Med Sci II

Tuesday, February 12, 2019

  • Victor Corces, Ph.D., Department of Biology, Emory University
    "Mechanisms of Transgenerational Inheritance of Obesity in Mice"
    3:00pm, West Lecture Hall - Med Sci II

Tuesday, March 26, 2019

  • Karen Reddy, Ph.D., Department of Biological Chemistry, John Hopkins Medicine
    "The Nuclear Lamina and Dynamic 3D Genome Organization"
    3:00pm, West Lecture Hall - Med Sci II

Tuesday, April 2, 2019

  • Geeta Narlikar, Ph.D., Department of Biochemistry and Biophysics, University of California, San Francisco
    "Phase-Separation and Allostery in Heterochromatin Regulation"
    3:00pm, West Lecture Hall - Med Sci II

Tuesday, April 16, 2019

  • D. Allan Drummond, Ph.D., Departments of Biochemistry & Molecular Biology and Human Genetics, University of Chicago
    "Stress or Signal? Rethinking the Cellular Response to Heat Shock"
    3:00pm, West Lecture Hall - Med Sci II

Fall 2018: Bedside to bench: Personalized Medicine through Basic Science

Tuesday, September 11, 2018

  • Introductory Lecture, Zhong Wang, PhD, Associate Professor of Cardiac Surgery, University of Michigan
    “Connecting Epigenetics and Tissue Engineering in Heart Protection and Regeneration”
    3:00pm, M3330 Med Sci I

Thursday, September 27, 2018

  • Michael C. Milone, MD, PhD, Associate Professor, Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine
    "Engineered T cell therapy for Cancer and Beyond"
    3:00pm, M3330 Med Sci I

Wednesday, October 3, 2018

  • Ali Khademhosseini, PhD Levi Knight Chair, Professor of Bioengineering, Radiology, Chemical and Biomolecular Engineering, UCLA
    “Emerging Organ Models and Organ Printing for Regenerative Medicine”
    3:00pm, 3695 North Lecture Hall, Med Sci II

 Tuesday, October 16, 2018

  • David Lillicrap, MD, FRCPC, Professor, Department of Pathology and Molecular Medicine, Queens University
    "Advances in the care of Inherited Bleeding Disorders through the Application of Molecular Science"
    3:00pm, M3330 Med Sci I

 Thursday, October 25, 2018

  • Stephen F. Badylak DVM, PhD, MD, Professor, Department of Surgery, Deputy Director of the McGowan Institute for Regenerative Medicine
    "Matrix Directed Cell Signaling for Regenerative Medicine Applications"
    3:00pm, M3330 Med Sci I

Winter 2018: Host-pathogen interactions: innate immunity and beyond

Thursday, February 22, 2018

  • Introductory Lecture, Mary O'Riordan, Ph.D., Department of Microbiology and Immunology, University of Michigan Medical School
    "Cells on fire: turning stress into inflammation"
    3:00pm, South Lecture Hall

Monday, March 5, 2018

  • Nels Elde, Ph.D., Department of Human Genetics, University of Utah
    "Evolutionary innovations from biological collisions"
    3:00pm, North Lecture Hall

Thursday, March 15, 2018

  • Blossom Damania, Ph.D., Department of Microbiology and Immunology, University of North Carolina at Chapel Hill
    "Modulation of cell signaling pathways by an oncogenic human herpesvirus"
    3:00pm, North Lecture Hall

Tuesday, March 20, 2018

  • Sara Sawyer, Ph.D., Molecular, Cellular, and Developmental Biology, University of Colorado, BioFrontiers Institute
    "Spillover: how viruses adapt at the animal - human interface"
    3:00pm, West Lecture Hall

Wednesday, April 4, 2018

  • Brian Lazzaro, Ph.D., Cornell Institute for Host-Microbe Interactions and Disease, Departments of Entomology and Ecology & Evolutionary Biology, Cornell University
    "Immune depression by mating and reproduction in Drosophila"
    3:00pm, North Lecture Hall

Fall 2017: You’re one in a million: techniques and applications of emerging single cell technologies

Tuesday, September 19, 2017

  • Introductory Lecture, Sue Hammoud, Ph.D., Departments of Human Genetics & Obstetrics & Gynecology, University of Michigan Medical School
    3:00pm, M3330 Med Sci I

Tuesday, September 26, 2017

  • Long Cai, Ph.D., Research Professor in Biology, California Institute of Technology
    “Spatial genomics: single cell in situ transcription profiling and lineage analysis”
    3:00pm, M3330 Med Sci I 
    Discussion:  4:00pm, 2813 Med Sci II

Tuesday, October 10, 2017

  • Alex Shalek, MA, A.M., Ph.D., Assistant Professor, Department of Chemistry, MIT School of Science
    "Approaching the immune system as an interacting ensemble of cells"
    3:00pm, M3330 Med Sci I
    Discussion: 4:00pm, 3813 Med Sci II

Tuesday, October 31, 2017

  • Bjorn Kafsack, Ph.D., MHS, Assistant Professor of Microbiology and Immunology, Weill Cornell Medical College
    "One is the loneliest number: single cell exploration of sexual commitment in malaria parasites"
    3:00pm, M3330 Med Sci I
    Discussion: 4:00pm, 3813 Med Sci II

Tuesday, November 28, 2017

  • Nick Navin, Ph.D., Associate Professor, Department of Genetics, The University of Texas MD Anderson Cancer Center
    "Delineating tumor evolution with single cell genomics"
    3:00pm, M3330 Med Sci I
    Discussion: 4:00pm, 3813 Med Sci II

Winter 2017: SEQ-ing the truth: leveraging functional genomics to gain insights into mechanisms of neurological disease

Wednesday, February 15, 2017

  • Introductory Lecture, Kenneth Kwan, Ph.D., Molecular & Behavioral Neuroscience Institute and Department of Human Genetics, University of Michigan Medical School
    "Genetics, genomics, and modeling; studying neurological diseases in the age of NGS"

Wednesday, February 22, 2017

  • Genevieve Konopka, Ph.D., Department of Neuroscience, University of Texas Southwestern Medical Center
    "Molecular networks of cognition"

Wednesday, March 8, 2017

  • Andrew McCallion, Ph.D., McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine
    "Exploring the cellular context of risk variants: neurological disorders, non-coding variation and cellular heterogeneity"

Tuesday, March 28, 2017

  • Gary Bassell, Ph.D., Department of Cell Biology, Emory University School of Medicine
    "Messenger RNA transport, local translation, and Fragile X syndrome"

Tuesday, April 11, 2017

  • Hugo Bellen, D.V.M., Ph.D., Departments of Molecular and Human Genetics & Neuroscience, Baylor College of Medicine
    "Flies as a diagnostic tool for human disease in the Undiagnosed Disease Network and for deciphering pathogenesis"

Fall 2016: Make yourself at home: how cells and organisms adapt to and define their micro-environments

Thursday, September 22, 2016

  • Introductory Lecture, Marina Pasca di Magliano, Ph.D., University of Michigan

Tuesday, October 11, 2016

  • Erika Matunis, Ph.D., Johns Hopkins School of Medicine
    "Stem cell dynamics in the Drosophila testis"

Tuesday, October 18, 2016

  • Raghu Kalluri, M.D., Ph.D., University of Texas MD Anderson Cancer Center
    "Exploiting exosomes biology for diagnosis and treatment of cancer"

Thursday, November 10, 2016

  • Lea Goentoro, Ph.D., California Institute of Technology
    "Self-repairing symmetry in jellyfish"

Thursday, November 17, 2016

  • Zena Werb, Ph.D., University of California, San Francisco
    "Understanding cancer, metastasis and the tumor microenvironment in the age of single-cell genomics"

Winter 2016: Chromosome biology: exploring the impacts of genome architecture

February 25, 2016

  • Jacob Mueller, Ph.D., Department of Human Genetics, University of Michigan Medical School
    “Two faces of the X chromosome: applications to chromosome structure and function”

March 8, 2016

  • Mohamed Noor, Ph.D., Department of Biology, Duke University
    “Recombination rate influences adaptation and speciation: studies in the Drosophila pseudoobscura species group”

March 29, 2016

  • Houra Merrikh, Ph.D., Department of Microbiology, University of Washington
    “Replication-transcription conflicts in bacteria”

April 5, 2016

  • Beth Sullivan, Ph.D., Department of Molecular Genetics & Microbiology, Duke University School of Medicine
    “Epigenetic basis of chromosome inheritance in humans”

April 12, 2016

  • Douglas Koshland, Ph.D., Department of Molecular & Cellular Biology, University of California, Berkeley
    “The good, the bad, and the ugly of chromosome structure”

Fall 2015: Engineering biology from proteins to patients

October 29, 2015

  • Nina Lu, Ph.D., Department of Chemical Engineering, University of Michigan
    “Engineering biology: from proteins to patients”

November 5, 2015

  • Jaquin Niles, M.D., Ph.D., Massachusetts Institute of Technology
    “Designing and integrating synthetic biology tools to study malaria”

November 12, 2015

  • Salil Lachke, Ph.D., University of Delaware
    “iSyTE: an integrative approach to study gene function in eye development”

November 19, 2015

  • Chris Voigt, Ph.D., Massachusetts Institute of Technology
    “Cello: a programming language for cells”

December 10, 2015

  • Timothy K. Lu, Ph.D., Massachusetts Institute of Technology
    “Engineering living cells for human health applications”

Winter 2015: Manipulating genomes: applications for basic science and disease

February 26, 2015

  • Thomas Saunders, Ph.D., University of Michigan
    "Introduction: principles of genome editing"

March 03, 2015

  • Paula Cannon, Ph.D. , University of Southern California 
    "Giving HIV the [zinc] finger: targeted nucleases and precision gene therapy"

March 17, 2015

  • Dirk Hockemeyer, Ph.D. , University of California, Berkeley 
    "Elucidating telomere function in human tumor biology"

March 27, 2015

  • J. Keith Joung, M.D., Ph.D. , Harvard Medical School 
    "Targeted genome and epigenome editing using CRISPR and TALE technologies"

April 07, 2015

  • Matthew Porteus, M.D., Ph.D. , Stanford School of Medicine 
    "Genome editing as a research and therapeutic tool"

Fall 2014: Movement: from molecule to man

September 23, 2014

  • Kristen J. Verhey, Ph.D., University of Michigan
    “Movement: from molecule to man”

September 30, 2014

  • P. Hande Ozdinler, Ph.D., Northwestern University
    "What do the upper motor neurons tell us about motor neuron diseases: let's listen to what they have to say"

October 9, 2014

  • Keith Burridge,Ph.D., University North Carolina-Chapel Hill
    “From cell adhesion and mechanotransduction to Rho GTPases”

October 30, 2014

  • Jan Lammerding, Ph.D., Cornell University
    “Squish and squeeze: nuclear biomechanics and mechanotransduction in health and disease”

November 18, 2014

  • Lee Sweeney, Ph.D., University of Pennsylvania 
    “Design and redesign of the molecular motor, myosin”

Winter 2014: Modern insights into evolutionary genetics

January 28, 2014

  • Patricia Wittkopp, Ph.D., University of Michigan
    "The genomic basis of regulatory evolution"

February 11, 2014

  • Manyuan Long, Ph.D. , University of Chicago  
    "New genes as drivers of phenotypic and functional evolution"

March 25, 2014

  • Harmit Singh Malik, Ph.D. , Fred Hutchinson Cancer Research Center 
    "Genetic conflicts: the usual suspects and beyond"

April 04, 2014

    • Jeffrey Palmer, Ph.D. , Indiana University, Bloomington 
      "Mitochondrial sex: rampant horizontal gene transfer in mitochondrial genomes"

Fall 2013: Evaluation and development of molecular therapies for cancer

October 1, 2013

  • Judith Leopold, Ph.D., University of Michigan
    “The evolution of MEK inhibitors from early discovery to regulatory approval and beyond”

October 8, 2013

  • Dane Compton, Ph.D., Dartmouth University
    “Mechanisms of chromosomal instability in human cancer cells”

October 24, 2013

  • Brian Ross, Ph.D., University of Michigan
    “Imaging biomarkers of cancer treatment response”

November 12, 2013

  • Frederic de Sauvage, Ph.D., Genentech Inc.
    "Targeting the hedgehog pathway in cancer: from bench to clinic"

November 26, 2013

  • Michael F. Clarke, Ph.D., Stanford University  
    “Translating basic science”

Winter 2013: Frontiers in gene regulation

January 23, 2013

  • Scott Barolo, Ph.D., University of Michigan
    "Gene regulation: why does it have to be so complicated?"

January 29, 2013

  • Luciano Marraffini, Ph.D. , The Rockefeller University  
    "The CRISPR-Cas adaptive immune system of bacteria: mechanism and applications"

February 20, 2013

  • John Stamatoyannopoulos, M.D. , University of Washington 
    "Gene regulation and common disease"

March 19, 2013

  • Karen Adelman, Ph.D., National Institute of Environmental Health Sciences 
    "Promoter-proximal pausing of RNA polymerase II: a window for opportunities"

Fall 2012: Wiring the nervous system in health and disease

September 25, 2012

  • Brian Pierchala, Ph.D., University of Michigan
    “Wiring the nervous system in health and disease”

September 27, 2012

  • Florian Engert, Ph.D., Harvard University
    “Sensory processing and motor control in the larval zebrafish”

November 13, 2012

  • John Flanagan, Ph.D., Harvard Medical School
    “Axon guidance and regeneration: transmembrane receptors and RNA-based regulation mechanisms”

November 27, 2012

  • Zhigang He, Ph.D., Children’s Hospital Boston  
    "Re-building neuronal circuits after CNS injury"

December 13, 2012

  • Martine F. Roussel, Ph.D., St. Jude Children’s Research Hospital – Univ of Tennessee
    “Molecular networks and cell of origin of pediatric medulloblastoma”