Genetics Training Program: Genetics Short Course

U-M Buhl Building

HUMGEN 630: Co-sponsored by the Genetics Training Program (GTP) and the Program in Cellular and Molecular Biology (CMB).

Fall and Winter terms, 1 credit each.

In this short course, GTP and CMB students invite outstanding internal and external scientists to give a seminar and to formally and informally interact with students.

The topic of the Winter 2019 Short Course, sponsored by Human Genetics, is “Contain Your Cells: Regulatory Design by Chromatin Organization and Phase Separation." See schedule below.

Seminars are open to the University Community

Winter 2019: Contain Your Cells: Regulatory Design by Chromatin Organization and Phase Separation

Tuesday, January 22, 2019

  • Introductory Lecture, Kaushik Ragunathan, Ph.D., Department of Biological Chemistry, University of Michigan Medical School
    “Phase Separation as an Organizing Principle of Cellular Function”
    3:00pm, West Lecture Hall - Med Sci II

Tuesday, February 12, 2019

  • Victor Corces, Ph.D., Department of Biology, Emory University
    "Mechanisms of Transgenerational Inheritance of Obesity in Mice"
    3:00pm, West Lecture Hall - Med Sci II

Tuesday, March 26, 2019

  • Karen Reddy, Ph.D., Department of Biological Chemistry, John Hopkins Medicine
    "The Nuclear Lamina and Dynamic 3D Genome Organization"
    3:00pm, West Lecture Hall - Med Sci II

Tuesday, April 2, 2019

  • Geeta Narlikar, Ph.D., Department of Biochemistry and Biophysics, University of California, San Francisco
    "Phase-Separation and Allostery in Heterochromatin Regulation"
    3:00pm, West Lecture Hall - Med Sci II

Tuesday, April 16, 2019

  • D. Allan Drummond, Ph.D., Departments of Biochemistry & Molecular Biology and Human Genetics, University of Chicago
    "Stress or Signal? Rethinking the Cellular Response to Heat Shock"
    3:00pm, West Lecture Hall - Med Sci II


Fall 2018: Bedside to bench: Personalized Medicine through Basic Science

Tuesday, September 11, 2018

  • Introductory Lecture, Zhong Wang, PhD, Associate Professor of Cardiac Surgery, University of Michigan
    “Connecting Epigenetics and Tissue Engineering in Heart Protection and Regeneration”
    3:00pm, M3330 Med Sci I

Thursday, September 27, 2018

  • Michael C. Milone, MD, PhD, Associate Professor, Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine
    "Engineered T cell therapy for Cancer and Beyond"
    3:00pm, M3330 Med Sci I

Wednesday, October 3, 2018

  • Ali Khademhosseini, PhD Levi Knight Chair, Professor of Bioengineering, Radiology, Chemical and Biomolecular Engineering, UCLA
    “Emerging Organ Models and Organ Printing for Regenerative Medicine”
    3:00pm, 3695 North Lecture Hall, Med Sci II

 Tuesday, October 16, 2018

  • David Lillicrap, MD, FRCPC, Professor, Department of Pathology and Molecular Medicine, Queens University
    "Advances in the care of Inherited Bleeding Disorders through the Application of Molecular Science"
    3:00pm, M3330 Med Sci I

 Thursday, October 25, 2018

  • Stephen F. Badylak DVM, PhD, MD, Professor, Department of Surgery, Deputy Director of the McGowan Institute for Regenerative Medicine
    "Matrix Directed Cell Signaling for Regenerative Medicine Applications"
    3:00pm, M3330 Med Sci I


Winter 2018: Host-pathogen interactions: innate immunity and beyond

Thursday, February 22, 2018

  • Introductory Lecture, Mary O'Riordan, Ph.D., Department of Microbiology and Immunology, University of Michigan Medical School
    "Cells on fire: turning stress into inflammation"
    3:00pm, South Lecture Hall

Monday, March 5, 2018

  • Nels Elde, Ph.D., Department of Human Genetics, University of Utah
    "Evolutionary innovations from biological collisions"
    3:00pm, North Lecture Hall

Thursday, March 15, 2018

  • Blossom Damania, Ph.D., Department of Microbiology and Immunology, University of North Carolina at Chapel Hill
    "Modulation of cell signaling pathways by an oncogenic human herpesvirus"
    3:00pm, North Lecture Hall

Tuesday, March 20, 2018

  • Sara Sawyer, Ph.D., Molecular, Cellular, and Developmental Biology, University of Colorado, BioFrontiers Institute
    "Spillover: how viruses adapt at the animal - human interface"
    3:00pm, West Lecture Hall

Wednesday, April 4, 2018

  • Brian Lazzaro, Ph.D., Cornell Institute for Host-Microbe Interactions and Disease, Departments of Entomology and Ecology & Evolutionary Biology, Cornell University
    "Immune depression by mating and reproduction in Drosophila"
    3:00pm, North Lecture Hall

Fall 2017: You’re one in a million: techniques and applications of emerging single cell technologies

Tuesday, September 19, 2017

  • Introductory Lecture, Sue Hammoud, Ph.D., Departments of Human Genetics & Obstetrics & Gynecology, University of Michigan Medical School
    3:00pm, M3330 Med Sci I

Tuesday, September 26, 2017

  • Long Cai, Ph.D., Research Professor in Biology, California Institute of Technology
    “Spatial genomics: single cell in situ transcription profiling and lineage analysis”
    3:00pm, M3330 Med Sci I 
    Discussion:  4:00pm, 2813 Med Sci II

Tuesday, October 10, 2017

  • Alex Shalek, MA, A.M., Ph.D., Assistant Professor, Department of Chemistry, MIT School of Science
    "Approaching the immune system as an interacting ensemble of cells"
    3:00pm, M3330 Med Sci I
    Discussion: 4:00pm, 3813 Med Sci II

Tuesday, October 31, 2017

  • Bjorn Kafsack, Ph.D., MHS, Assistant Professor of Microbiology and Immunology, Weill Cornell Medical College
    "One is the loneliest number: single cell exploration of sexual commitment in malaria parasites"
    3:00pm, M3330 Med Sci I
    Discussion: 4:00pm, 3813 Med Sci II

Tuesday, November 28, 2017

  • Nick Navin, Ph.D., Associate Professor, Department of Genetics, The University of Texas MD Anderson Cancer Center
    "Delineating tumor evolution with single cell genomics"
    3:00pm, M3330 Med Sci I
    Discussion: 4:00pm, 3813 Med Sci II

Winter 2017: SEQ-ing the truth: leveraging functional genomics to gain insights into mechanisms of neurological disease

Wednesday, February 15, 2017

  • Introductory Lecture, Kenneth Kwan, Ph.D., Molecular & Behavioral Neuroscience Institute and Department of Human Genetics, University of Michigan Medical School
    "Genetics, genomics, and modeling; studying neurological diseases in the age of NGS"

Wednesday, February 22, 2017

  • Genevieve Konopka, Ph.D., Department of Neuroscience, University of Texas Southwestern Medical Center
    "Molecular networks of cognition"

Wednesday, March 8, 2017

  • Andrew McCallion, Ph.D., McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine
    "Exploring the cellular context of risk variants: neurological disorders, non-coding variation and cellular heterogeneity"

Tuesday, March 28, 2017

  • Gary Bassell, Ph.D., Department of Cell Biology, Emory University School of Medicine
    "Messenger RNA transport, local translation, and Fragile X syndrome"

Tuesday, April 11, 2017

  • Hugo Bellen, D.V.M., Ph.D., Departments of Molecular and Human Genetics & Neuroscience, Baylor College of Medicine
    "Flies as a diagnostic tool for human disease in the Undiagnosed Disease Network and for deciphering pathogenesis"

Fall 2016: Make yourself at home: how cells and organisms adapt to and define their micro-environments

Thursday, September 22, 2016

  • Introductory Lecture, Marina Pasca di Magliano, Ph.D., University of Michigan

Tuesday, October 11, 2016

  • Erika Matunis, Ph.D., Johns Hopkins School of Medicine
    "Stem cell dynamics in the Drosophila testis"

Tuesday, October 18, 2016

  • Raghu Kalluri, M.D., Ph.D., University of Texas MD Anderson Cancer Center
    "Exploiting exosomes biology for diagnosis and treatment of cancer"

Thursday, November 10, 2016

  • Lea Goentoro, Ph.D., California Institute of Technology
    "Self-repairing symmetry in jellyfish"

Thursday, November 17, 2016

  • Zena Werb, Ph.D., University of California, San Francisco
    "Understanding cancer, metastasis and the tumor microenvironment in the age of single-cell genomics"

Winter 2016: Chromosome biology: exploring the impacts of genome architecture

February 25, 2016

  • Jacob Mueller, Ph.D., Department of Human Genetics, University of Michigan Medical School
    “Two faces of the X chromosome: applications to chromosome structure and function”

March 8, 2016

  • Mohamed Noor, Ph.D., Department of Biology, Duke University
    “Recombination rate influences adaptation and speciation: studies in the Drosophila pseudoobscura species group”

March 29, 2016

  • Houra Merrikh, Ph.D., Department of Microbiology, University of Washington
    “Replication-transcription conflicts in bacteria”

April 5, 2016

  • Beth Sullivan, Ph.D., Department of Molecular Genetics & Microbiology, Duke University School of Medicine
    “Epigenetic basis of chromosome inheritance in humans”

April 12, 2016

  • Douglas Koshland, Ph.D., Department of Molecular & Cellular Biology, University of California, Berkeley
    “The good, the bad, and the ugly of chromosome structure”

Fall 2015: Engineering biology from proteins to patients

October 29, 2015

  • Nina Lu, Ph.D., Department of Chemical Engineering, University of Michigan
    “Engineering biology: from proteins to patients”

November 5, 2015

  • Jaquin Niles, M.D., Ph.D., Massachusetts Institute of Technology
    “Designing and integrating synthetic biology tools to study malaria”

November 12, 2015

  • Salil Lachke, Ph.D., University of Delaware
    “iSyTE: an integrative approach to study gene function in eye development”

November 19, 2015

  • Chris Voigt, Ph.D., Massachusetts Institute of Technology
    “Cello: a programming language for cells”

December 10, 2015

  • Timothy K. Lu, Ph.D., Massachusetts Institute of Technology
    “Engineering living cells for human health applications”

Winter 2015: Manipulating genomes: applications for basic science and disease

February 26, 2015

  • Thomas Saunders, Ph.D., University of Michigan
    "Introduction: principles of genome editing"

March 03, 2015

  • Paula Cannon, Ph.D. , University of Southern California 
    "Giving HIV the [zinc] finger: targeted nucleases and precision gene therapy"

March 17, 2015

  • Dirk Hockemeyer, Ph.D. , University of California, Berkeley 
    "Elucidating telomere function in human tumor biology"

March 27, 2015

  • J. Keith Joung, M.D., Ph.D. , Harvard Medical School 
    "Targeted genome and epigenome editing using CRISPR and TALE technologies"

April 07, 2015

  • Matthew Porteus, M.D., Ph.D. , Stanford School of Medicine 
    "Genome editing as a research and therapeutic tool"

Fall 2014: Movement: from molecule to man

September 23, 2014

  • Kristen J. Verhey, Ph.D., University of Michigan
    “Movement: from molecule to man”

September 30, 2014

  • P. Hande Ozdinler, Ph.D., Northwestern University
    "What do the upper motor neurons tell us about motor neuron diseases: let's listen to what they have to say"

October 9, 2014

  • Keith Burridge,Ph.D., University North Carolina-Chapel Hill
    “From cell adhesion and mechanotransduction to Rho GTPases”

October 30, 2014

  • Jan Lammerding, Ph.D., Cornell University
    “Squish and squeeze: nuclear biomechanics and mechanotransduction in health and disease”

November 18, 2014

  • Lee Sweeney, Ph.D., University of Pennsylvania 
    “Design and redesign of the molecular motor, myosin”

Winter 2014: Modern insights into evolutionary genetics

January 28, 2014

  • Patricia Wittkopp, Ph.D., University of Michigan
    "The genomic basis of regulatory evolution"

February 11, 2014

  • Manyuan Long, Ph.D. , University of Chicago  
    "New genes as drivers of phenotypic and functional evolution"

March 25, 2014

  • Harmit Singh Malik, Ph.D. , Fred Hutchinson Cancer Research Center 
    "Genetic conflicts: the usual suspects and beyond"

April 04, 2014

    • Jeffrey Palmer, Ph.D. , Indiana University, Bloomington 
      "Mitochondrial sex: rampant horizontal gene transfer in mitochondrial genomes"

Fall 2013: Evaluation and development of molecular therapies for cancer

October 1, 2013

  • Judith Leopold, Ph.D., University of Michigan
    “The evolution of MEK inhibitors from early discovery to regulatory approval and beyond”

October 8, 2013

  • Dane Compton, Ph.D., Dartmouth University
    “Mechanisms of chromosomal instability in human cancer cells”

October 24, 2013

  • Brian Ross, Ph.D., University of Michigan
    “Imaging biomarkers of cancer treatment response”

November 12, 2013

  • Frederic de Sauvage, Ph.D., Genentech Inc.
    "Targeting the hedgehog pathway in cancer: from bench to clinic"

November 26, 2013

  • Michael F. Clarke, Ph.D., Stanford University  
    “Translating basic science”

Winter 2013: Frontiers in gene regulation

January 23, 2013

  • Scott Barolo, Ph.D., University of Michigan
    "Gene regulation: why does it have to be so complicated?"

January 29, 2013

  • Luciano Marraffini, Ph.D. , The Rockefeller University  
    "The CRISPR-Cas adaptive immune system of bacteria: mechanism and applications"

February 20, 2013

  • John Stamatoyannopoulos, M.D. , University of Washington 
    "Gene regulation and common disease"

March 19, 2013

  • Karen Adelman, Ph.D., National Institute of Environmental Health Sciences 
    "Promoter-proximal pausing of RNA polymerase II: a window for opportunities"

Fall 2012: Wiring the nervous system in health and disease

September 25, 2012

  • Brian Pierchala, Ph.D., University of Michigan
    “Wiring the nervous system in health and disease”

September 27, 2012

  • Florian Engert, Ph.D., Harvard University
    “Sensory processing and motor control in the larval zebrafish”

November 13, 2012

  • John Flanagan, Ph.D., Harvard Medical School
    “Axon guidance and regeneration: transmembrane receptors and RNA-based regulation mechanisms”

November 27, 2012

  • Zhigang He, Ph.D., Children’s Hospital Boston  
    "Re-building neuronal circuits after CNS injury"

December 13, 2012

  • Martine F. Roussel, Ph.D., St. Jude Children’s Research Hospital – Univ of Tennessee
    “Molecular networks and cell of origin of pediatric medulloblastoma”