Carey Lumeng

Carey Lumeng, M.D., Ph.D.

Professor of Internal Medicine, Division of Pediatrics and Communicable Diseases
Professor, Molecular and Integrative Physiology
Accepting Students?
Yes

Biography

I am a Pediatrician physician scientist with an interest in the mechanisms by which obesity negatively impacts health and disease. I completed MD PhD training at the University of Michigan Medical Scientist Training Program followed by Residency at Boston Children's Hospital. I returned for clinical fellowship and training in obesity science and adipose tissue biology.

Research Interests

Current Projects:

1. Adipose tissue macrophages (ATMs) as antigen presenting cells - Studies are underway to evaluate communication between macrophage and T cells in fat and how these pathways regulate nutrient metabolism.

2. Mechanisms of ATM activation - With obesity, ATMs take on a pro-inflammatory profile. The mechanisms of this relates to chemokine mediated monocyte trafficking to fat and knockout mice are utilized to identify the critical pathways.

3. Interaction between nutrients and macrophage inflammation - The mechanisms why which nutrients influence inflammation are being explored. This includes the effects of fatty acids, glucose, adipokines, lipids, and stress hormones on the action of macrophage, dendritic cells, and lymphocytes that can explain the inflammatory activation with obesity.