Emily Yarosz

Immunology Program Graduate Student Candidate

Biography

Emily graduated from the Pennsylvania State University in 2016 with a B.S. in Immunology and Infectious Disease. While at PSU, she worked in the lab of Dr. Robert Paulson as an undergraduate researcher studying hematopoietic cell development and stress erythropoeisis. Emily entered the Graduate Program in Immunology in the Fall of 2016, and she later joined the lab of Dr. Cheong-Hee Chang for her thesis work. 

Research Interests

Cellular metabolism is critical in regulating the responses of various immune cells to infection. As such, the Chang lab aims to better understand how different metabolic pathways drive adaptive immune responses. My thesis work focuses on understanding how the E3 ubiquitin ligase Cullin 3 (Cul3) interacts with intracellular metabolic processes to influence the proliferation, activation, and development of effector functions in both naive CD4 T cells and invariant natural killer T (iNKT) cells.

Techniques

T cell-specific murine models, tamoxifen-inducible Cre-ERT2 systems, Flow Cytometry, FACS, Western Blot, qPCR, Seahorse assay

Awards

2021 - Outstanding Graduate Service Award, Graduate Program in Immunology, University of Michigan

2020 - The Herman & Dorothy Miller Award for Innovative Immunology Research

2020 - AAI Trainee Abstract Award, AAI - IMMUNOLOGY 2020

2018 - AAI Young Investigator Award, Autumn Immunology Conference

Abstracts

1. Yarosz, E.L. and C.H. Chang. Novel roles for Cullin 3 in naïve CD4 T cell homeostasis and activation. AAI – IMMUNOLOGY 2021. Virtual conference. May 2021. (Poster Presentation)

2. Yarosz, E.L. and C.H. Chang. Novel roles for Cullin 3 in T cell-mediated immune responses. AAI – IMMUNOLOGY 2020. Honolulu, HI. May 2020. (Oral and Poster Presentation)*
*Conference was canceled due to COVID-19 pandemic

3. Yarosz, E.L., Ye, C., Kumar, A., and C.H. Chang. Novel roles for Cullin 3 in modulating CD4 T cell-mediated immune responses. University of Michigan Graduate Program in Immunology Annual Retreat. Oregon, OH. June 2019. (Oral Presentation)

4. Yarosz, E.L. and C.H. Chang. Understanding the role of Cullin 3 in NKT cell peripheral maintenance. Autumn Immunology Conference. Chicago, IL. November 2018. (Oral and Poster Presentations)

5. Yarosz, E.L., Kumar, A., Ye, C., Seo, Y.A., and C.H. Chang. Iron as an essential regulator of CD4 T cell proliferation and function. University of Michigan Microbiology and Immunology Departmental Retreat. Hickory Corners, MI. October 2018. (Poster Presentation)

 

Hobbies and Extracurricular Activities

When she's not in the lab, Emily loves to bake, read, and explore downtown Ann Arbor with friends.