Erin Holcomb

Immunology Program Graduate Student Candidate


Erin graduated from The Ohio State University in 2020 with a B.S. and Research Distinction in Microbiology. During her time at OSU, Erin worked in the lab of Dr. Abhay Satoskar researching the immune mechanisms and vaccine development of the parasitic disease Leishmaniasis. In the summer of 2019, she completed an internship at LSU Health Shreveport under Dr. Rona Scott where she studied the role of Retinoblastoma protein in HPV16/EBV-induced oral malignancies. Erin joined the Immunology graduate program at the University of Michigan in 2021 to pursue her graduate work in the lab of Mike Green, with Weiping Zou as her co-mentor.

Research Interests

Erin is interested in CD8+ T cell fate and function in cancer. Her work is focused on identifying genetic regulators which cause T cell dysfunction and better understanding if modulating these factors can improve the efficacy of immunotherapy.


CRISPR/Cas9, lentiviral transduction, flow cytometry, cloning, RT-qPCR, western blot, bioinformatics, animal husbandry


Holcomb E, Jiang L, Tate A, Pearson A, Wang Z, Jungles K, James J, Huber A, Green M. “CRISPR-Cas9 screen identifies potential novel regulators of CD8+ T cell dysfunction.” American Association of Immunologists Annual Meeting, Washington, DC. May 2023. Poster presentation.


2020 – Undergraduate Research Fellowship
2020 – Research Distinction in Microbiology

Hobbies and Extracurricular Activities

Outside of lab, Erin enjoys cooking, reading, lifting, and exploring outdoors.