Jadie Moon

Immunology Program Graduate Student Pre-Candidate

Biography

Jadie graduated from the University of California, Berkeley in 2019 with a BA in Molecular and Cellular Biology with an emphasis on Immunology and Pathology. She spent 2 years at the Joint Bioenergy Institute during her undergraduate years in Jay Keasling's lab. Her research focused on optimizing microorganism engineering to develop tools for synthetic biology.

After graduation, she joined an industry lab in a biotech company called Xcell Biosciences in San Francisco where she worked as an Assay Development Specialist for 2 years. At Xcell Biosciences, she investigated the effects of the tumor microenvironment on gene/protein expression profile, physiology, and functionality of cancer cell lines, primary tumor cells, and primary immune cells. Jadie joined the University of Michigan in 2021 to pursue her PhD in Immunology.

Research Interests

Epigenetic regulation of keratinocyte function in normal and pathologic skin repair

Techniques Used

Murine models of wound repair, human skin tissue processing, immune and structural cell isolation from wounds by flow sorting and Chromatin Immunoprecipitation (ChIP) analysis, cell culture and other basic techniques

Abstracts

1. Lu Q., Li Y., Wong A., Moon J., Lim J. Short-term culture under pressurized and hypoxic conditions reduces hematopoietic stem cell apoptosis and improves cellular function of transplant products. International Society of Cellular Therapy, 2020. Abstract 3393060.

2. Moon J., Wehrs M., Prahl JP., Li Y., Tanjore D., Keasling J., Pray T., Mukhopadhyay A. Respiratory metabolic state drives the efficiency of heterologous production pathway in S.
Cerevisiae. Joint Bioenergy Institute Undergraduate Poster Session, 2018.

3. Moon J., Wehrs M., Platz L., Laus B., Mukhopadhyay A., Keasling J. Production of blue
pigments in S. cerevisiae as indication of Non-Ribosomal Peptide Production. Joint Bioenergy Institute Undergraduate Poster Session, 2018.

4. Azad A., Laus B., Moon J., Wehrs M., Barajas J., Bolonio D., Haushalter B., Keasling J. Exploring the effects of chromosomal position on gene expression in Escherichia coli. Joint Bioenergy Institute Undergraduate Poster Session, 2017.

Awards

Rose Hills Foundation Science and Engineering Scholarship (Awarded Fall 2018 – Spring 2019)

Publications

1. Wehrs M, Prahl JP, Moon J, Li Y, Tanjore D, Keasling JD, Pray T, Mukhopadhyay A. Production efficiency of the bacterial non-ribosomal peptide indigoidine relies on the respiratory metabolic state in S. cerevisiae. Microb Cell Fact. 2018 Dec 13;17(1):193. doi: 10.1186/s12934-018-1045-1.

2. Wehrs M, Gladden JM, Liu Y, Platz L, Prahl JP, Moon J, Papa G, Sundstrom E, Geiselman GM, Tanjore D, Keasling JD, Pray TR, Simmons BA, Mukhopadhyay A. Sustainable bioproduction of the blue pigment indigoidine: Expanding the range of heterologous products in R. toruloides to include non-ribosomal peptides. Green Chemistry. 2019 June 17;21(12), 3394–3406. https://doi.org/10.1039/c9gc00920e

3. Wehrs M, Thompson MG, Banerjee D, Prahl JP, Morella NM, Barcelos CA, Moon J, Costello Z, Keasling JD, Shih PM, Tanjore D, Mukhopadhyay A. Investigation of Bar-seq as a method to study population dynamics of Saccharomyces cerevisiae deletion library during bioreactor cultivation. Microb Cell Fact. 2020 Aug 18;19(1):167. doi: 10.1186/s12934-020-01423-z.

Hobbies and Extracurricular Activities

Baking, running, cooking, and photography