Jeffrey L. Platt, MD, is Director of the Transplantation Biology Program and Professor of Surgery, and Microbiology and Immunology at the University of Michigan. He was educated in medicine and trained in pediatrics, nephrology, immunology and immunopathology. Dr. Platt’s research includes fundamental investigation of the physiology and pathophysiology of the immune system in transplantation, malignancy and infectious disease. Current projects include investigation aimed at identifying the inherited and acquired determinants of immune fitness and novel approaches to restoring immunological fitness and developing new ways of replacing organ function and protecting tissues against immune and toxic injury and infection. Dr. Platt has authored more than 600 papers, 4 books and numerous patents. He is an active member of the Association of American Physicians and the National Academy of Medicine, among other organizations.
Current research probes inherited and acquired determinants of immune fitness, approaches to restoring immune fitness and development new ways of replacing organ function and protecting tissues against immune and toxic injury and infection. Titles of some current grants include "donor-specific B cells in transplantation, TNRSF13B polymorphism and the control of innate B cell responses, mutable vaccines for emerging infectious threats and effect of peritransplant C3d blockade and ischemia on chronic rejection and vasculopathy in an experimental model of VCA.