Jeffrey Platt, M.D., Ph.D.

Professor of Surgery
Professor of Microbiology and Immunology

Biography

Dr. Platt was educated in medicine and trained in pediatrics, nephrology and immunopathology. He has conducted research in immunology, cell biology, transplantation, experimental therapeutics and related fields, leading to publication of 600 papers, 3 books, numerous patents and disclosures, a MERIT AWARD from the NIH and election to the National Academy of Medicine and the Association of American Physicians, among others and to the coveted BOOT award. Dr. Platt is widely known for his investigation of novel approaches to replacing the function of organs, especially the application of genetic engineering toward that end, and for elucidating mechanisms of by which immunity injures blood vessels and organs, and for discovering the process by which tissues and organs acquire resistance to immune-mediated injury (named accommodation).

Research Interests

Dr. Platt's current investigations focus on cellular and molecular mechanisms of accommodation, inherited determinants of immune fitness and host defense, antigen-specific B cell responses to transplantation, evolutionary and cellular mechanisms of gene diversification in health, disease and therapeutics.