I graduated from Tulane University in 2018 with a double major B.S. in Cellular and Molecular Biology and Chemistry. During my time at Tulane, I was an undergraduate researcher working on characterizing a novel class of antibiotics. I am now at the University of Michigan as a Ph.D. student in the Program in Immunology.
My project in Dr. Daniel Goldstein’s laboratory focuses on how aging dysregulates the immune response to influenza infection. My broad research interests include immunology, senescence, host-pathogen interactions, and pulmonology.
Flow cytometry, Viral plaque assay, ELISA, Microscopy, Western blot, Primary cell culture, Intranasal infections, In vivo models
George Lucry Grant -2017
Jonathan Ching Undergraduate Summer Fellowship -2017
Ann Hero Northrup Award in Chemistry -2018
Research Training in Experimental Immunology (T32) Trainee -2019
Rackham Graduate Student Pre-Candidate Research Grant -2020
Ruth L. Kirschstein Predoctoral Individual National Research Service Award (NHLBI, F31) - 2021
Excellence in Basic Science Award (EBSA) - 2021
"Age-associated elevations in prostaglandin E2 enhance mortality to influenza infection", Program in Immunology Annual Retreat, University of Michigan, Ann Arbor, MI (2021)
Gilroy DW, De Maeyer RPH, Tepper M, O'Brien A, Uddin M, Chen J, Goldstein DR, Akbar AN. Treating exuberant, non-resolving inflammation in the lung; Implications for acute respiratory distress syndrome and COVID-19. Pharmacol Ther. 2021 May;221:107745. doi: 10.1016/j.pharmthera.2020.107745. Epub 2020 Nov 11. Review. PubMed PMID: 33188794; PubMed Central PMCID: PMC7657264.
Penke LR, Speth JM, Draijer C, Zaslona Z, Chen J, Mancuso P, Freeman CM, Curtis JL, Goldstein DR, Peters-Golden M. PGE2 accounts for bidirectional changes in alveolar macrophage self-renewal with aging and smoking. Life Sci Alliance. 2020 Nov;3(11). doi: 10.26508/lsa.202000800. Print 2020 Nov. PubMed PMID: 32820026; PubMed Central PMCID: PMC7441521.
Chen J, Kelley WJ, Goldstein DR. Role of Aging and the Immune Response to Respiratory Viral Infections: Potential Implications for COVID-19. J Immunol. 2020 Jul 15;205(2):313-320. doi: 10.4049/jimmunol.2000380.
Smith CA, Kulkarni U, Chen J, Goldstein DR. Influenza virus inoculum volume is critical to elucidate age-dependent mortality in mice. Aging Cell. 2019 Apr;18(2):e12893. doi: 10.1111/acel.12893.
Hobbies and Extracurricular Activities
During my free time, I enjoy painting and trying out new restaurants. I also enjoy spending relaxing nights crocheting and hanging out with my two cats.