I am a Vascular Surgeon with a robust basic science lab supported by R01 funding as well as foundation grants.
I have had a long-standing defined clinical and translational interest in the mechanisms underlying impaired diabetic wound healing. My long-term goal is to uncover the basic mechanisms responsible for the coordination of immune cells in early tissue repair processes, determine impairments in Type 2 Diabetes and translate this knowledge to the bedside.
My research has focused on histone methylation changes in bone marrow progenitor cells and the impact on peripheral macrophage phenotypes as it relates to wound healing and inflammation. This work will provide important data on inflammatory macrophages in peripheral tissue and their contribution to chronic inflammation and may lead to novel treatment modalities.
Research Opportunities for Rotating Students
Potential rotation projects involve the regulation of inflammation in innate immune cells post-surgery and projects to understand how innate immune cell activity is regulated by metabolic changes.