Kole Tison

Kole Tison

Immunology Program Graduate Student Candidate


I hold a B.S. in Cell Biology and Neuroscience with a minor in Genetics and honors from Montana State University. I worked in Steven Stowers' Neurobiology lab studying dual-neurotransmission from 2017-2019 culminating in a publication in G3. During the summers of 2016 and 2017 I interned at Rocky Mountain Laboratories in Heinz Feldman's laboratory of Virology where I learned molecular cloning, cell tissue culture and a pseudotype neutralization assay. After graduating in 2019, I worked in Ethan Shevach's Cellular Immunology lab at the NIH as a post-baccalaureate research fellow until the summer of 2021.

Research Interests

My current research focuses on elucidating immunogenic pathways in the tumor microenvironment and how these are altered by post-translational modifications of signaling transducers such as STAT1. My previous research in Ethan Shevach's Cellular Immunology lab focused on the role of the Helios transcription factor in T cell subsets- mainly comparing its function in Foxp3+ Tregs and conventional CD4+ T cells in transgenic TCR murine models. My undergraduate research work explored a genetic-based neurophenotyping tool developed in drosophila to characterize mono and dual-neurotransmitter neurons in the visual system.

Techniques Used

Immunoprecipitation, western blotting, PCR, flow cytometry, tissue culture, T cell adoptive transfer, scRNAseq analysis, gel electrophoresis, IFC, tissue genotyping, cryosection, drosophila and murine dissection protocols, and select biochemistry-based assays.

Hobbies and Extracurricular Activities

Rollerblading and climbing