I received my B.S. in Biotechnology from the Lanzhou University - China in 2006, and my Ph.D. in Biochemistry and Molecular Biology from Peking Union Medical College/Tsinghua University in 2011.
My research interests have been to identify the key elements for chemotherapeutic resistance in ovarian cancer microenvironment at both molecular and cellular levels. I explore the impact of fibroblasts and immune cells on cisplatin resistance and sensitivity in ovarian cancer cells and identify that effector T cells abrogate fibroblasts-mediated cisplatin resistance. This finding provides a scientific rationale for the combination of chemotherapy and immunotherapy.
Flow cytometry, tissue culture, Western Blot, qPCR, ChIP-PCR