Lab Life

Shannon Estadt, BS, a graduate student in Dr. Kahlenberg’s lab, received the Student Achievement Award from the Rheumatology Research Foundation to present her abstract “Interferon Alpha Promotes Caspase-Dependent Apoptosis Independently of Reactive Oxygen Species in Ultraviolet B Exposed Keratinocytes” at the 2019 ACR Annual Meeting.

Ms. Estadt is working to understand the cell death pathways that are activated in keratinocytes by type I interferons and ultraviolet (UV) light to gain a better understanding of why patients with lupus experience photosensitivity. She has found that priming keratinocytes with interferons prior to exposure to UV light promotes caspase-8-dependent apoptosis, suggesting that interferon-driven extrinsic apoptosis may contribute to photosensitive responses. This work will hopefully lead to new treatments for SLE patients whose disease is flared by the sun.

Undergraduate student,Tyson Moore, receives a ribbon for his poster at the annual Undergraduate Research Opportunity Program (UROP) Research Spring Symposium.

Postdoctoral fellow, Sirisha Sirobhushanam, PhD, standing with undergraduate student, Josh Banfield, while he presents his work.

Sonya Wolf-Fortune, PhD, an Immunology Program Graduate Student and research assistant in Dr. Kahlenberg's lab, presented her thesis "The role of Type I Interferons in TLR7-Mediated Lupus and UVB-Induced Immune Cell Responses" on April 22, 2019.

Sonya Wolf-Fortune, PhD, with mentor, J. Michelle Kahlenberg, MD, PhD.

Sonya Wolf-Fortune & Shannon Estadt take a much needed break.

A favorite t-shirt among the Kahlenberg lab members.

2018 Team Meeting at Kahlenberg Farm

L to R: Jianhua Liu, Grace Hile, Sonya Wolf-Fortune, Shannon Estadt, Nazy Gharaee-Kermani, Sirisha Sirobhushanam, J. Michelle Kahlenberg, Tamra Reed, Jessica Turnier.