Publications

Highlights

Adenosine Receptor Agonism Protects Against NETosis and Thrombosis in Antiphospholipid Syndrome
Ali, Ramadan A., Gandhi, Alex A., Meng, He, Yalavarthi, Srilakshmi, Vreede, Andrew P., Estes, Shanea K., Palmer, Olivia R., Bockenstedt, Paula L., Pinsky, David J., Greve, Joan M., Diaz, Jose A., Kanthi, Yogendra, Knight, Jason S. Nature Communications. 2019 April 23

Ectonucleotidase-Mediated Suppression of Lupus Autoimmunity and Vascular Dysfunction
Knight JS, Mazza LF, Yalavarthi S, Sule G, Ali RA, Hodgin JB, Kanthi Y, Pinsky DJ. Front Immunol. 2018 Jun 11;9:1322

Activated Signature of Antiphospholipid Syndrome Neutrophils Reveals Potential Therapeutic Target
Knight JS, Meng H, Coit P, Yalavarthi S, Sule G, Gandhi AA, Grenn RC, Mazza LF, Ali RA, Renauer P, Wren JD, Bockenstedt PL, Wang H, Eitzman DT, Sawalha AH. JCI Insight. 2017 Sep 21;2(18). pii: 93897

In Vivo Role of Neutrophil Extracellular Traps in Antiphospholipid Antibody-Mediated Venous Thrombosis
Meng H, Yalavarthi S, Kanthi Y, Mazza LF, Elfline MA, Luke CE, Pinsky DJ, Henke PK, Knight JS. Arthritis Rheumatol. 2017 Mar;69(3):655-667

Endothelial Progenitor Dysfunction Associates with a Type I Interferon Signature in Primary Antiphospholipid Syndrome
Grenn RC, Yalavarthi S, Gandhi AA, Kazzaz NM, Núñez-Álvarez C, Hernández-Ramírez D, Cabral AR, McCune WJ, Bockenstedt PL, Knight JS. Ann Rheum Dis. 2017 Feb;76(2):450-457

Treatment of Catastrophic Antiphospholipid Syndrome
Kazzaz NM, McCune WJ, Knight JS. Curr Opin Rheumatol. 2016 May;28(3):218-27

Systemic Lupus Erythematosus Complicated by Diffuse Alveolar Haemorrhage: Risk factors, Therapy and Survival
Kazzaz NM, Coit P, Lewis EE, McCune WJ, Sawalha AH, Knight JS. Lupus Sci Med. 2015 Sep 23;2(1):e000117

Release of Neutrophil Extracellular Traps by Neutrophils Stimulated with Antiphospholipid Antibodies: A Newly Identified Mechanism of Thrombosis in the Antiphospholipid Syndrome
Yalavarthi S, Gould TJ, Rao AN, Mazza LF, Morris AE, Núñez-Álvarez C, Hernández-Ramírez D, Bockenstedt PL, Liaw PC, Cabral AR, Knight JS. Arthritis Rheumatol. 2015 Nov;67(11):2990-3003

Peptidylarginine Deiminase Inhibition Disrupts NET Formation and Protects Against Kidney, Skin and Vascular Disease in Lupus-Prone MRL/lpr Mice
Knight JS, Subramanian V, O'Dell AA, Yalavarthi S, Zhao W, Smith CK, Hodgin JB, Thompson PR, Kaplan MJ. Ann Rheum Dis. 2015 Dec;74(12):2199-206

Peptidylarginine Deiminase Inhibition Reduces Vascular Damage and Modulates Innate Immune Responses in Murine Models of Atherosclerosis
Knight JS, Luo W, O'Dell AA, Yalavarthi S, Zhao W, Subramanian V, Guo C, Grenn RC, Thompson PR, Eitzman DT, Kaplan MJ. Circ Res. 2014 Mar 14;114(6):947-56

Peptidylarginine Deiminase Inhibition Is Immunomodulatory and Vasculoprotective in Murine Lupus
Knight JS, Zhao W, Luo W, Subramanian V, O'Dell AA, Yalavarthi S, Hodgin JB, Eitzman DT, Thompson PR, Kaplan MJ. J Clin Invest. 2013 Jul;123(7):2981-93